Yang Pei, Zhang Xiu-Zhen, Zhang Keqin, Tang Zihui
Department of Tumor Internal Medicine, The Tumor Hospital Affiliated to Central South China University Changsha, Hunan, China.
Department of Endocrinology and Metabolism, Shanghai Tongji Hospital, Tongji University School of Medicine China.
Int J Clin Exp Med. 2015 Sep 15;8(9):15958-66. eCollection 2015.
This study was aimed at estimating the associations between coffee intake and osteoporosis (OP) in Chinese postmenopausal women.
We conducted a large-scale, community-based, cross-sectional study to investigate the associations by using self-report questionnaire to access frequency of coffee intake. The total of 1817 participants was available to data analysis in this study. Multiple regression models controlling for confounding factors to include frequency of coffee intake variable were performed to investigate the relationships for OP.
Positive correlations between frequency of meat food intake and T-score were reported (β = 0.216, P value < 0.001). Multiple regression analysis indicated that the frequency of meat food intake was significantly associated with OP (P < 0.05 for model 1 and model 2). The postmenopausal women with high frequency of meat food intake had a lower prevalence of OP.
The findings indicated that frequency of coffee intake was independently and significantly associated with OP. The prevalence of OP was more frequent in Chinese postmenopausal women not preferring coffee habits.
本研究旨在评估中国绝经后女性咖啡摄入量与骨质疏松症（OP）之间的关联。
我们开展了一项大规模的、基于社区的横断面研究，通过使用自我报告问卷来获取咖啡摄入频率，以调查两者之间的关联。本研究共有1817名参与者可供数据分析。我们进行了控制混杂因素（包括咖啡摄入频率变量）的多元回归模型，以研究与OP的关系。
报告显示肉类食物摄入频率与T值之间存在正相关（β = 0.216，P值<0.001）。多元回归分析表明，肉类食物摄入频率与OP显著相关（模型1和模型2的P<0.05）。肉类食物摄入频率高的绝经后女性OP患病率较低。
研究结果表明，咖啡摄入频率与OP独立且显著相关。不喜欢喝咖啡的中国绝经后女性中OP患病率更高。
