齐多夫定的临床药代动力学。当前数据概述。 - Suppr

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超能文献

Clinical pharmacokinetics of zidovudine. An overview of current data.

作者信息

Collins J M, Unadkat J D

机构信息

Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, Maryland.

出版信息

Clin Pharmacokinet. 1989 Jul;17(1):1-9. doi: 10.2165/00003088-198917010-00001.

DOI:10.2165/00003088-198917010-00001

PMID:2663302

Abstract

摘要

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Clinical pharmacokinetics of zidovudine. An overview of current data.齐多夫定的临床药代动力学。当前数据概述。

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Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.抗癌药物在小鼠、大鼠、仓鼠、狗、猴和人类中毒性的定量比较。

Cancer Chemother Rep. 1966 May;50(4):219-44.

Plasma and cerebrospinal fluid pharmacokinetics of 3'-azido-3'-deoxythymidine: a novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases.3'-叠氮-3'-脱氧胸苷的血浆和脑脊液药代动力学：一种具有治疗艾滋病及相关疾病潜在应用价值的新型嘧啶类似物。

Clin Pharmacol Ther. 1987 Apr;41(4):407-12. doi: 10.1038/clpt.1987.49.

Toxicity of 3'-azido-3'-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for normal human hematopoietic progenitor cells in vitro.3'-叠氮-3'-脱氧胸苷和9-(1,3-二羟基-2-丙氧甲基)鸟嘌呤对正常人造血祖细胞的体外毒性

Antimicrob Agents Chemother. 1987 Mar;31(3):452-4. doi: 10.1128/AAC.31.3.452.

3'-azido-3'-deoxythymidine. An unusual nucleoside analogue that permeates the membrane of human erythrocytes and lymphocytes by nonfacilitated diffusion.3'-叠氮-3'-脱氧胸苷。一种不寻常的核苷类似物，通过非易化扩散穿透人红细胞和淋巴细胞的膜。

J Biol Chem. 1987 Apr 25;262(12):5748-54.

Pyrimidine dideoxyribonucleosides: selectivity of penetration into cerebrospinal fluid.

J Pharmacol Exp Ther. 1988 May;245(2):466-70.

The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial.齐多夫定（AZT）治疗艾滋病及艾滋病相关综合征患者的毒性。一项双盲、安慰剂对照试验。

N Engl J Med. 1987 Jul 23;317(4):192-7. doi: 10.1056/NEJM198707233170402.

The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial.叠氮胸苷（AZT）治疗艾滋病及艾滋病相关综合征患者的疗效。一项双盲、安慰剂对照试验。

N Engl J Med. 1987 Jul 23;317(4):185-91. doi: 10.1056/NEJM198707233170401.

Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection.齐多夫定（AZT）持续静脉输注对有症状HIV感染儿童的影响。

N Engl J Med. 1988 Oct 6;319(14):889-96. doi: 10.1056/NEJM198810063191401.

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Am J Med. 1988 Aug 29;85(2A):189-94.

Zidovudine overdosage.齐多夫定过量用药。

Ann Intern Med. 1988 Jul 1;109(1):76-7. doi: 10.7326/0003-4819-109-1-76.

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