Roopan Selvaraj Mohana, Devi Rajeswari V, Kalpana V N, Elango G
Chemistry of Heterocycles & Natural Product Research Laboratory, Organic Chemistry Division, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632014, India.
Biomolecules and Genetics Division, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, 632014, India.
Appl Microbiol Biotechnol. 2016 Feb;100(3):1153-1162. doi: 10.1007/s00253-015-7190-0. Epub 2015 Dec 5.
Bottle gourd (Lagenaria siceraria) belongs to the family Cucurbitaceae, which comprises about 118 genera and 825 species. It is an important vegetable crop of India, and its production is influenced by a number of factors viz., environmental, nutritional, cultural operation and use of plant growth regulators. Since, bottle gourd belongs to a medicinal family, it plays a major role in the treatment of several diseases related to the skin and heart. There are several organic chemical compounds including vitamin B complex, pectin, dietary soluble fibres, ascorbic acid, beta-carotene, amino acids and minerals which have been isolated from this species. Therefore, the bottle gourd is considered to have a great impact on therapeutic health benefits. Due to drastic industrialization and urbanization, most of the human beings are facing several ill effects which may lead to death at extreme cases. Hence, the major research area was said to be nanotechnology. Taking into consideration, we have combined nanotechnology field with waste source in the name of green synthesis and planned to cure several diseases, as most of the researchers focused their work on this and succeeded too. The present study is a complete review of L. siceraria that covers the ethnomedical uses, chemical constituents, and pharmacological profile. This study is mainly focused on the antibacterial, hepatoprotective, diuretic and anthelminthic activities.
葫芦（Lagenaria siceraria）属于葫芦科，该科约有118个属和825个物种。它是印度一种重要的蔬菜作物，其产量受多种因素影响，即环境、营养、栽培操作和植物生长调节剂的使用。由于葫芦属于药用植物科，它在治疗几种与皮肤和心脏相关的疾病中发挥着重要作用。已经从该物种中分离出几种有机化合物，包括复合维生素B、果胶、膳食可溶性纤维、抗坏血酸、β-胡萝卜素、氨基酸和矿物质。因此，葫芦被认为对治疗健康有益。由于工业化和城市化的急剧发展，大多数人正面临着一些不良影响，在极端情况下可能导致死亡。因此，主要的研究领域据说就是纳米技术。考虑到这一点，我们以绿色合成的名义将纳米技术领域与废物来源相结合，并计划治愈几种疾病，因为大多数研究人员都专注于这方面的工作并且也取得了成功。本研究是对葫芦的全面综述，涵盖了民族医学用途、化学成分和药理学特征。本研究主要关注抗菌、保肝、利尿和驱虫活性。
