Wong Adam C-N, Holmes Andrew, Ponton Fleur, Lihoreau Mathieu, Wilson Kenneth, Raubenheimer David, Simpson Stephen J
Charles Perkins Centre, The University of Sydney , Sydney, NSW, Australia ; School of Biological Sciences, The University of Sydney , Sydney, NSW, Australia ; Division of Infectious Diseases, Boston Children's Hospital, Harvard Medical School , Boston, MA, USA.
Charles Perkins Centre, The University of Sydney , Sydney, NSW, Australia ; School of Biological Sciences, The University of Sydney , Sydney, NSW, Australia ; School of Molecular Bioscience, The University of Sydney , Sydney, NSW, Australia.
Front Microbiol. 2015 Nov 27;6:1359. doi: 10.3389/fmicb.2015.01359. eCollection 2015.
The role of microbes as a part of animal systems has historically been an under-appreciated aspect of animal life histories. Recently, evidence has emerged that microbes have wide-ranging influences on animal behavior. Elucidating the complex relationships between host-microbe interactions and behavior requires an expanded ecological perspective, involving the host, the microbiome and the environment; which, in combination, is termed the holobiont. We begin by seeking insights from the literature on host-parasite interactions, then expand to consider networks of interactions between members of the microbial community. A central aspect of the environment is host nutrition. We describe how interactions between the nutrient environment, the metabolic and behavioral responses of the host and the microbiome can be studied using an integrative framework called nutritional geometry, which integrates and maps multiple aspects of the host and microbial response in multidimensional nutrient intake spaces.
微生物作为动物系统一部分的作用，在历史上一直是动物生活史中一个未得到充分重视的方面。最近，有证据表明微生物对动物行为有着广泛影响。阐明宿主 - 微生物相互作用与行为之间的复杂关系需要一个扩展的生态学视角，涉及宿主、微生物组和环境；这三者结合起来被称为全生物。我们首先从关于宿主 - 寄生虫相互作用的文献中寻求见解，然后扩展到考虑微生物群落成员之间的相互作用网络。环境的一个核心方面是宿主营养。我们描述了如何使用一种称为营养几何学的综合框架来研究营养环境、宿主和微生物组的代谢及行为反应之间的相互作用，该框架在多维营养摄入空间中整合并描绘了宿主和微生物反应的多个方面。
