法国南部海鸥奇异变形杆菌分离株中携带blaCMY-2的SXT/R391相关整合与接合元件的高流行率
High Prevalence of SXT/R391-Related Integrative and Conjugative Elements Carrying blaCMY-2 in Proteus mirabilis Isolates from Gulls in the South of France.
作者信息
Aberkane Salim, Compain Fabrice, Decré Dominique, Dupont Chloé, Laurens Chrislène, Vittecoq Marion, Pantel Alix, Solassol Jérôme, Carrière Christian, Renaud François, Brieu Nathalie, Lavigne Jean-Philippe, Bouzinbi Nicolas, Ouédraogo Abdoul-Salam, Jean-Pierre Hélène, Godreuil Sylvain
机构信息
Centre Hospitalier Régional Universitaire (CHRU) de Montpellier, Département de Bactériologie-Virologie, Montpellier, France Université Montpellier 1, Montpellier, France INSERM U 1058, Infection by HIV and by Agents with Mucocutaneous Tropism: From Pathogenesis to Prevention, Montpellier, France
Sorbonne University, UPMC Université Paris 06, CR7, CIMI, Team E13 (Bacteriology), Paris, France INSERM U1135, CIMI, Team E13, Paris, France.
出版信息
Antimicrob Agents Chemother. 2015 Dec 7;60(2):1148-52. doi: 10.1128/AAC.01654-15. Print 2016 Feb.
The genetic structures involved in the dissemination of blaCMY-2 carried by Proteus mirabilis isolates recovered from different gull species in the South of France were characterized and compared to clinical isolates. blaCMY-2 was identified in P. mirabilis isolates from 27/93 yellow-legged gulls and from 37/65 slender-billed gulls. It was carried by a conjugative SXT/R391-like integrative and conjugative element (ICE) in all avian strains and in 3/7 human strains. Two clinical isolates had the same genetic background as six avian isolates.
对从法国南部不同鸥类物种中分离出的奇异变形杆菌携带的blaCMY-2传播所涉及的遗传结构进行了表征，并与临床分离株进行了比较。在27/93只黄腿鸥和37/65只细嘴鸥的奇异变形杆菌分离株中鉴定出blaCMY-2。在所有禽类菌株和3/7个人类菌株中，它由一种接合性SXT/R391样整合和接合元件（ICE）携带。两个临床分离株与六个禽类分离株具有相同的遗传背景。
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