Kitzerow Janina, Teufel Karoline, Wilker Christian, Freitag Christine M
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Autism Research and Intervention Center of Excellence Frankfurt, University hospital, Goethe-Universität Frankfurt am Main.
Autism Res. 2016 Sep;9(9):940-50. doi: 10.1002/aur.1588. Epub 2015 Dec 8.
To date no reliable and objective, change sensitive instrument for autistic symptoms is available. The brief observation of social communication change (BOSCC) was specifically developed to measure change of core autistic symptoms, for example, for use as outcome measure in early intervention trials. This study investigated quality criteria of a preliminary research version of the BOSCC in N = 21 children with autism spectrum disorder (ASD) who had participated for 1 year in the Frankfurt early intervention program (FFIP). BOSCC rating was done on play based ADOS video scenes. Inter-rater agreement on the BOSCC average total was very high. The BOSCC showed a significant decrease of autistic symptoms after 1 year with a medium effect size. Symptom specific improvements were captured by the social communication subscale and most single items. The BOSCC showed comparable change sensitivity to other autism specific instruments. Future studies should focus on the finalized BOSCC version, and replicate findings in a larger sample. Autism Res 2016, 9: 940-950. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.
迄今为止,尚无可靠、客观且对变化敏感的用于测量自闭症症状的工具。社会沟通变化简短观察法(BOSCC)是专门为测量自闭症核心症状的变化而开发的,例如用作早期干预试验中的结果指标。本研究调查了BOSCC初步研究版本在N = 21名患有自闭症谱系障碍(ASD)的儿童中的质量标准,这些儿童参加了为期1年的法兰克福早期干预项目(FFIP)。BOSCC评分基于ADOS游戏视频场景进行。评估者间在BOSCC平均总分上的一致性非常高。1年后,BOSCC显示出自闭症症状显著下降,效应量中等。社交沟通子量表及大多数单项指标捕捉到了症状的具体改善情况。BOSCC显示出与其他自闭症专用工具相当的变化敏感性。未来的研究应聚焦于最终版的BOSCC,并在更大样本中重复这些发现。《自闭症研究》2016年,9卷:940 - 950页。© 2015国际自闭症研究协会,威利期刊公司