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跨情境考察治疗结果：儿童基线特征如何影响治疗反应的衡量？

Examining Treatment Outcomes Across Contexts: How Do Child Baseline Characteristics Impact Measurement of Treatment Response?

机构信息

Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.

Program for Early Autism Research Leadership and Service (PEARLS), University of North Carolina, Chapel Hill, NC, USA.

出版信息

J Autism Dev Disord. 2023 Nov;53(11):4121-4131. doi: 10.1007/s10803-022-05655-3. Epub 2022 Aug 15.

DOI:10.1007/s10803-022-05655-3
PMID:35969334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9969996/
Abstract

The evaluation of the overlap between the ADOS BOSCC and Standard BOSCC as well as the exploration of child characteristics that may predict change are important steps in consolidating data-driven definitions of "improvement". Participants were seen between 2 and 5 times with Standard BOSCC and ADOS BOSCC observations over the course of early intervention trials (Grzadzinski et al. in J Autism Dev Disord 46:2464, 2016; Kim et al. in Autism 23:5, 2019). Results showed consistency between the Standard BOSCC and ADOS BOSCC, highlighting the utility of both as metrics of change and treatment outcome across contexts. Baseline characteristics may play a role in the tailoring of early intervention to maximize treatment outcome and may offer guidance when determining which outcome measures to use.

摘要

评估 ADOS BOSCC 与标准 BOSCC 的重叠情况，以及探索可能预测变化的儿童特征，是巩固基于数据的“改善”定义的重要步骤。在早期干预试验中，参与者接受了 2 到 5 次标准 BOSCC 和 ADOS BOSCC 观察（Grzadzinski 等人，J Autism Dev Disord 46:2464, 2016；Kim 等人，Autism 23:5, 2019）。结果表明，标准 BOSCC 和 ADOS BOSCC 之间具有一致性，突出了这两者作为跨环境变化和治疗结果的衡量标准的实用性。基线特征可能在为最大限度地提高治疗效果而定制早期干预中发挥作用，并在确定使用哪些结果测量时提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/0241033f4009/nihms-1869113-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/0e330771b6d9/nihms-1869113-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/6683914eec52/nihms-1869113-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/a48b42c7e49d/nihms-1869113-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/0241033f4009/nihms-1869113-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/0e330771b6d9/nihms-1869113-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/6683914eec52/nihms-1869113-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/a48b42c7e49d/nihms-1869113-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c78/9969996/0241033f4009/nihms-1869113-f0004.jpg

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