Gengoux Grace W, Paszek Katherine, Millan Maria Estefania, Gong Jared, Goodman Rebecca, Guillory Sasha, Baldi Gina, Libove Robin, Phillips Jennifer M, Hardan Antonio Y
Stanford University School of Medicine, Stanford, USA.
Department of Psychiatry & Behavioral Sciences, Division of Child & Adolescent Psychiatry, 401 Quarry Road, Stanford, CA, 94305-5719, USA.
J Autism Dev Disord. 2025 Jun 9. doi: 10.1007/s10803-025-06904-x.
Developmental social pragmatic interventions for autism spectrum disorder (ASD) focus on development of strong interpersonal relationships by encouraging social communication during joint play routines. The goal of the current investigation was to conduct a randomized controlled 24-week pilot trial to examine the efficacy of a Developmental Reciprocity Treatment package (DRT-P), a developmentally-based intervention that includes both parent training and direct treatment with the child, compared to a delayed treatment group (DTG). Thirty-seven children aged 2-5 years with ASD and language delay were randomized. 83% of parents in DRT-P met fidelity of implementation criteria by 24 weeks. Controlling for fidelity, participants in DRT-P showed significantly greater improvement on the Social Responsiveness Scale Total Score (F = 5.00; p = 0.034) and the Clinical Global Impressions Improvement scale; however no significant group differences were observed on the Brief Observation of Social Communication Change, Vineland Adaptive Behavior Scales, or the MacArthur-Bates Communicative Development Inventories. Findings suggest DRT is a promising intervention for improving some aspects of social functioning in young children with ASD. Future research exploring how behavioral and developmental interventions can be optimally combined to target core social difficulties along with adaptive and functional communication skills is expected to be beneficial.
针对自闭症谱系障碍（ASD）的发展性社会语用干预旨在通过在联合游戏活动中鼓励社交沟通来培养牢固的人际关系。本研究的目的是进行一项为期24周的随机对照试验，以检验发展性互惠治疗方案（DRT-P）的疗效，DRT-P是一种基于发展的干预措施，包括家长培训和对儿童的直接治疗，并与延迟治疗组（DTG）进行比较。37名年龄在2至5岁、患有ASD且有语言延迟的儿童被随机分组。到24周时，DRT-P组83%的家长达到了实施保真度标准。在控制保真度的情况下，DRT-P组的参与者在社会反应量表总分（F = 5.00；p = 0.034）和临床总体印象改善量表上有显著更大的改善；然而，在社会沟通变化简要观察、文兰适应行为量表或麦克阿瑟-贝茨沟通发展量表上未观察到显著的组间差异。研究结果表明，DRT是一种有前景的干预措施，可改善患有ASD的幼儿社会功能的某些方面。预计未来探索如何将行为和发展性干预最佳结合以针对核心社会困难以及适应性和功能性沟通技能的研究将是有益的。
