Julayanont Parunyou, Tangwongchai Sookjaroen, Hemrungrojn Solaphat, Tunvirachaisakul Chawit, Phanthumchinda Kammant, Hongsawat Juntanee, Suwichanarakul Panida, Thanasirorat Saowaluck, Nasreddine Ziad S
Division of Neurology, Department of Internal Medicine, Chulalongkorn University, Bangkok, Thailand.
MoCA Clinic and Institute, Greenfield Park, Quebec, Canada.
J Am Geriatr Soc. 2015 Dec;63(12):2550-2554. doi: 10.1111/jgs.13820. Epub 2015 Dec 9.
To assess the validity of a newly developed cognitive screening tool, the Montreal Cognitive Assessment-Basic (MoCA-B), in screening for mild cognitive impairment (MCI) in elderly adults with low education and varying literacy.
Cross-sectional.
Community hospital in Bangkok, Thailand.
Cognitively normal controls (n = 43) and individuals with MCI according to the National Institute on Aging-Alzheimer's Association work group criteria (n = 42) aged 55 to 80 with less than 5 years of education.
MoCA-B scores.
Mean MoCA-B scores were 26.3 ± 1.6 for illiterate controls and 21.3 ± 3.8 for illiterate participants with MCI (P < .001) and 26.6 ± 2.0 for literate controls and 23.0 ± 2.1 for literate participants with MCI (P < .001). MoCA-B scores did not differ significantly according to literacy, and multiple regression suggested no association with age or education. The optimal cutoff score of 24 out of 25 yielded 81% sensitivity and 86% specificity for MCI (area under the receiver operating characteristic curve = 0.90, P < .001). Test-retest reliability was 0.91 (P < .001), and internal consistency was 0.82. Administration time was 15 to 21 minutes.
The MoCA-B appears to have excellent validity and addresses an unmet need by accurately screening for MCI in poorly educated older adults regardless of literacy.
评估新开发的认知筛查工具——蒙特利尔认知评估基础版(MoCA - B)在筛查低教育水平和不同识字能力的老年人轻度认知障碍(MCI)方面的有效性。
横断面研究。
泰国曼谷的社区医院。
认知功能正常的对照组(n = 43)和根据美国国立衰老研究所 - 阿尔茨海默病协会工作组标准诊断为MCI的个体(n = 42),年龄在55至80岁之间,受教育年限少于5年。
MoCA - B得分。
文盲对照组的MoCA - B平均得分为26.3 ± 1.6,文盲MCI参与者为21.3 ± 3.8(P <.001);识字对照组为26.6 ± 2.0,识字MCI参与者为23.0 ± 2.1(P <.001)。MoCA - B得分在识字能力方面无显著差异,多元回归分析表明与年龄或教育程度无关。25分中24分的最佳截断分数对MCI的敏感性为81%,特异性为86%(受试者工作特征曲线下面积 = 0.90,P <.001)。重测信度为0.91(P <.001),内部一致性为0.82。施测时间为15至21分钟。
MoCA - B似乎具有出色的有效性,满足了一项未被满足的需求,即无论识字能力如何,都能准确筛查受教育程度低的老年人中的MCI。