Vaiman Michael, Abuita Rani, Bekerman Inessa
Department of Otolaryngology-Head and Neck Surgery, Assaf Harofe Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Zerifin 70300, Israel.
Department of Radiology, Assaf Harofe Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Zerifin 70300, Israel.
Int J Ophthalmol. 2015 Dec 18;8(6):1240-4. doi: 10.3980/j.issn.2222-3959.2015.06.30. eCollection 2015.
To measure optic nerve sheath diameters (ONSD) in different locations by computer tomography (CT) and to recommend the best location for cases when ONSD is used for intracranial pressure monitoring.
In a prospective cohort study, CT data of 300 healthy adults were analyzed (600 eyes). In all cases, the CT investigation was performed at the Emergency Department because of the various conditions that proved not to be connected with ophthalmological or neurological pathology. The ONSD were measured at 3 mm and 8 mm distance from the globe, and 3 mm from the anterior opening of the optic canal. The correlation analysis was performed with gender, age, and ethnic background.
The right/left ONSD are 4.94±1.51/5.17±1.34 mm at 3 mm, 4.35±0.76/4.45±0.62 mm at 8 mm from the globe, and 3.55±0.82/3.65±0.7 mm at 3 mm from the optic canal. No significant differences correlated with gender of the patients, their age, and ethnic background were found.
In healthy persons, the ONSD varies from 5.17±1.34 mm to 3.55±0.82 mm in different locations within the intraorbital space. The most stable results with lesser standard deviation can be obtained if it is measured 8-10 mm from the globe.
通过计算机断层扫描（CT）测量不同位置的视神经鞘直径（ONSD），并为将ONSD用于颅内压监测的病例推荐最佳测量位置。
在一项前瞻性队列研究中，分析了300名健康成年人的CT数据（600只眼）。所有病例均因各种经证实与眼科或神经病理学无关的病症在急诊科进行CT检查。在距眼球3毫米和8毫米处以及距视神经管前口3毫米处测量ONSD。对性别、年龄和种族背景进行相关性分析。
在距眼球3毫米处，右侧/左侧ONSD分别为4.94±1.51/5.17±1.34毫米；在距眼球8毫米处，分别为4.35±0.76/4.45±0.62毫米；在距视神经管3毫米处，分别为3.55±0.82/3.65±0.7毫米。未发现与患者性别、年龄和种族背景相关的显著差异。
在健康人中，眶内空间不同位置的ONSD在5.17±1.34毫米至3.55±0.82毫米之间变化。如果在距眼球8 - 10毫米处测量，可获得标准差较小且最稳定的结果。
