头颈部外科医生的调强放射治疗
Intensity-modulated radiotherapy for head and neck surgeons.
作者信息
Gutiontov Stanley I, Shin Edward J, Lok Benjamin, Lee Nancy Y, Cabanillas Ruben
机构信息
Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
Department of Otolaryngology/Head and Neck Surgery, New York Eye and Ear Infirmary of Mount Sinai, New York, New York.
出版信息
Head Neck. 2016 Apr;38 Suppl 1(Suppl 1):E2368-73. doi: 10.1002/hed.24338. Epub 2015 Dec 26.
Abstract
The development of intensity-modulated radiotherapy (IMRT) has played a major role in improving outcomes and decreasing morbidity in patients with head and neck cancer. This review addresses this vital modality with a focus on the important role of the head and neck surgeon. The technique as well as its benefits and points of caution are outlined, the definitions of tumor and treatment volumes are discussed, and the dose and fractionation are detailed. Following this are several sections dedicated to the role of the head and neck surgeon in the planning of both definitive and postoperative radiotherapy to the primary site and neck. There is a focus throughout on anatomic and surgical considerations; commonly encountered situations are illustrated. With a deeper understanding of this technique and their own pivotal contribution to target delineation, head and neck surgeons will be poised to expand their role and improve cancer care for their patients. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2368-E2373, 2016.
摘要
调强放射治疗（IMRT）的发展在改善头颈部癌患者的治疗效果和降低发病率方面发挥了重要作用。本综述探讨了这一重要模式，重点关注头颈外科医生的重要作用。文中概述了该技术及其益处和注意事项，讨论了肿瘤体积和治疗体积的定义，并详细说明了剂量和分割方式。接下来有几个部分专门论述了头颈外科医生在原发部位和颈部的根治性放疗及术后放疗计划中的作用。全文重点关注解剖学和手术方面的考虑因素，并举例说明了常见情况。通过更深入地了解这项技术以及他们自身对靶区勾画的关键贡献，头颈外科医生将有能力扩大其作用，改善对患者的癌症治疗。© 2015威利期刊公司。《头颈》38: E2368 - E2373, 2016年。
相似文献
1
Intensity-modulated radiotherapy for head and neck surgeons.头颈部外科医生的调强放射治疗
Head Neck. 2016 Apr;38 Suppl 1(Suppl 1):E2368-73. doi: 10.1002/hed.24338. Epub 2015 Dec 26.
2
[Target volume delineation for head and neck cancer intensity-modulated radiotherapy].[头颈部癌调强放射治疗的靶区勾画]
Cancer Radiother. 2011 Oct;15(6-7):466-72. doi: 10.1016/j.canrad.2011.07.239. Epub 2011 Aug 30.
3
Swallowing-sparing intensity-modulated radiotherapy for head and neck cancer patients: treatment planning optimization and clinical introduction.吞咽 sparing 强度调制放疗在头颈部癌症患者中的应用：治疗计划优化与临床应用。
Radiother Oncol. 2013 Jun;107(3):282-7. doi: 10.1016/j.radonc.2013.05.004. Epub 2013 Jun 3.
4
Delineating neck targets for intensity- modulated radiation therapy of head and neck cancer. What we learned from marginal recurrences?确定头颈癌调强放射治疗的颈部靶区。我们从边缘复发中学到了什么？
Front Radiat Ther Oncol. 2007;40:193-207. doi: 10.1159/000106036.
5
Intensity Modulated Radiotherapy (IMRT) in head and neck cancers - an overview.头颈部癌症的调强放射治疗（IMRT）——综述
Gulf J Oncolog. 2012 Jul(12):17-26.
6
Dynamic intensity-modulated non-coplanar arc radiotherapy (INCA) for head and neck cancer.头颈部癌的动态调强非共面弧形放射治疗（INCA）
Radiother Oncol. 2006 Nov;81(2):151-7. doi: 10.1016/j.radonc.2006.09.004. Epub 2006 Oct 19.
7
Unknown primary head and neck cancer treated with intensity-modulated radiation therapy: to what extent the volume should be irradiated.头颈部不明原发灶癌采用调强放疗治疗：照射范围应多大。
Oral Oncol. 2009 Jun;45(6):474-9. doi: 10.1016/j.oraloncology.2008.06.006. Epub 2008 Sep 18.
8
Radiobiological basis and clinical results of the simultaneous integrated boost (SIB) in intensity modulated radiotherapy (IMRT) for head and neck cancer: A review.头颈部癌症调强放疗（IMRT）中同时整合增敏（SIB）的放射生物学基础和临床结果：综述。
Crit Rev Oncol Hematol. 2010 Feb;73(2):111-25. doi: 10.1016/j.critrevonc.2009.03.003. Epub 2009 May 5.
9
Delineating neck targets for intensity-modulated radiation therapy of head and neck cancer.
Front Radiat Ther Oncol. 2011;43:255-270. doi: 10.1159/000322444. Epub 2011 May 20.
10
Evaluation of unified intensity-modulated arc therapy for the radiotherapy of head-and-neck cancer.对头颈部癌放射治疗中统一调强弧形治疗的评估。
Radiother Oncol. 2016 May;119(2):331-6. doi: 10.1016/j.radonc.2016.03.010. Epub 2016 Mar 31.
引用本文的文献
1
Diffuse choroidal hemangioma: Ophthalmic outcomes following intensity-modulated radiation therapy.弥漫性脉络膜血管瘤：调强放射治疗后的眼科结局
Taiwan J Ophthalmol. 2025 Mar 10;15(1):103-108. doi: 10.4103/tjo.TJO-D-24-00139. eCollection 2025 Jan-Mar.
2
Analysis of ADR reports of cetuximab based on the FDA adverse event reporting system database.基于美国食品药品监督管理局不良事件报告系统数据库的西妥昔单抗不良反应报告分析
Sci Rep. 2025 Feb 3;15(1):4104. doi: 10.1038/s41598-025-88838-z.
3
Correlation of degree of acute radiation dermatitis (RD) with skin dose distribution in head and neck squamous cell carcinoma patients treated with definitive concurrent chemoradiation.接受根治性同步放化疗的头颈部鳞状细胞癌患者中急性放射性皮炎（RD）程度与皮肤剂量分布的相关性
Rep Pract Oncol Radiother. 2024 Dec 4;29(5):579-587. doi: 10.5603/rpor.102824. eCollection 2024.
4
Three Cases of Persistent Laryngeal Edema Postradiation Therapy.放疗后持续性喉水肿三例
Anesth Prog. 2024 May 3;71(1):24-28. doi: 10.2344/anpr-70-03-06.
5
Factors Contributing to Postoperative Radiotherapy Delays in Head and Neck Cancer: A Comprehensive Review.头颈部癌术后放疗延迟的相关因素：一项综述
Cureus. 2024 Aug 19;16(8):e67240. doi: 10.7759/cureus.67240. eCollection 2024 Aug.
6
Virtual tumor mapping and margin control with 3-D planning and navigation.采用三维规划与导航技术进行虚拟肿瘤映射及边界控制。
Innov Surg Sci. 2024 Apr 25;9(1):17-24. doi: 10.1515/iss-2021-0009. eCollection 2024 Mar.
7
Activation of gelatinases in permanent human teeth after different experimental radiotherapy protocols.不同实验性放射治疗方案后永久性人牙中明胶酶的激活。
Braz Dent J. 2023 Nov-Dec;34(6):130-139. doi: 10.1590/0103-6440202305542.
8
Osteoradionecrosis of the Jaw Following Proton Radiation Therapy for Patients With Head and Neck Cancer.头颈部癌症质子放射治疗后颌骨放射性骨坏死。
JAMA Otolaryngol Head Neck Surg. 2023 Feb 1;149(2):151-159. doi: 10.1001/jamaoto.2022.4165.
9
A Case of Gorham-Stout Disease of the Skull Base Treated With Intensity Modulated Radiation Therapy.1例采用调强放射治疗的颅底戈谢病病例。
Adv Radiat Oncol. 2021 Sep 29;7(1):100809. doi: 10.1016/j.adro.2021.100809. eCollection 2022 Jan-Feb.
10
Evaluation of computed tomography settings in the context of visualization and discrimination of low dose injections of a novel liquid soft tissue fiducial marker in head and neck imaging.评估在头颈部成像中使用新型液体软组织基准标记物进行低剂量注射时的 CT 扫描参数，以实现可视化和区分效果。
BMC Med Imaging. 2021 Oct 27;21(1):157. doi: 10.1186/s12880-021-00689-y.
本文引用的文献
1
Imaging for head and neck cancer.头颈部癌症的影像学检查
Surg Oncol Clin N Am. 2015 Jul;24(3):455-71. doi: 10.1016/j.soc.2015.03.012. Epub 2015 Apr 16.
2
Cancer stem cells and field cancerization of oral squamous cell carcinoma.口腔鳞状细胞癌的癌症干细胞与场癌化
Oral Oncol. 2015 Jul;51(7):643-51. doi: 10.1016/j.oraloncology.2015.04.006. Epub 2015 Apr 23.
3
Radiation-induced fibrosis: mechanisms and implications for therapy.辐射诱导的纤维化：机制及其对治疗的影响
J Cancer Res Clin Oncol. 2015 Nov;141(11):1985-94. doi: 10.1007/s00432-015-1974-6. Epub 2015 Apr 25.
4
Patterns of spread of head and neck adenoid cystic carcinoma.头颈部腺样囊性癌的扩散模式
Clin Radiol. 2015 Jun;70(6):644-53. doi: 10.1016/j.crad.2015.01.013. Epub 2015 Mar 11.
5
Patterns of lymph node metastasis from nasopharyngeal carcinoma based on the 2013 updated consensus guidelines for neck node levels.基于2013年颈部淋巴结分区更新共识指南的鼻咽癌淋巴结转移模式
Radiother Oncol. 2015 Apr;115(1):41-5. doi: 10.1016/j.radonc.2015.02.017. Epub 2015 Mar 5.
6
A prospective phase 2 trial of reirradiation with stereotactic body radiation therapy plus cetuximab in patients with previously irradiated recurrent squamous cell carcinoma of the head and neck.一项关于立体定向体部放射治疗联合西妥昔单抗对先前接受过放疗的头颈部复发性鳞状细胞癌患者进行再照射的前瞻性2期试验。
Int J Radiat Oncol Biol Phys. 2015 Mar 1;91(3):480-8. doi: 10.1016/j.ijrobp.2014.11.023. Epub 2015 Jan 30.
7
Final long-term results of a phase I/II study of dose-escalated intensity-modulated radiotherapy for locally advanced laryngo-hypopharyngeal cancers.局部晚期喉下咽癌剂量递增调强放疗I/II期研究的最终长期结果
Oral Oncol. 2014 Nov;50(11):1089-97. doi: 10.1016/j.oraloncology.2014.07.018. Epub 2014 Sep 6.
8
Eliminating radiotherapy to the contralateral retropharyngeal and high level II lymph nodes in head and neck squamous cell carcinoma is safe and improves quality of life.对头颈鳞状细胞癌行对侧咽后及高位 II 区淋巴结放疗的消除是安全的，并能提高生活质量。
Cancer. 2014 Dec 15;120(24):3994-4002. doi: 10.1002/cncr.28938. Epub 2014 Aug 20.
9
The frequency of re-planning and its variability dependent on the modification of the re-planning criteria and IGRT correction strategy in head and neck IMRT.在头颈部调强适形放疗中，重新计划的频率及其可变性取决于重新计划标准和 IGRT 校正策略的修改。
Radiat Oncol. 2014 Aug 11;9:175. doi: 10.1186/1748-717X-9-175.
10
Cochlea sparing effects of intensity modulated radiation therapy in head and neck cancers patients: a long-term follow-up study.调强放疗对头颈部肿瘤患者耳蜗保护作用的长期随访研究。
J Otolaryngol Head Neck Surg. 2014 Aug 6;43(1):30. doi: 10.1186/s40463-014-0030-x.
Zotero 插件