Laužikienė D, Ramašauskaitė D, Lūža T, Lenkutienė R
Obstetrics and Gynaecology Centre, Vilnius University Hospital SantariškiųKlinikos, Vilnius, Lithuania ; Obstetrics and Gynaecology Clinic, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Obstetrics and Gynaecology Clinic, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Geburtshilfe Frauenheilkd. 2015 Nov;75(11):1167-1171. doi: 10.1055/s-0035-1558131.
Autoimmune haemolytic anaemia (AIHA), caused primarily by pregnancy, is poorly described in the literature. There is especially little information on coping with cases that are not responsive to glucocorticoid treatment, monitoring a fetal condition, and identifying fetal haemolytic anaemia as early as possible. A case of pregnancy-induced autoimmune haemolytic anaemia is reported with major problems in differential diagnosis, treatment and the risks posed to both the mother and the fetus. The anaemia went into spontaneous remission of the disease several weeks after delivery. Autoimmune haemolytic anaemia is rarely reported in literature, but can be dangerous for both fetus and mother. It therefore should be described and discussed among obstetricians and gynaecologists, and the etiopathogenesis should be further studied.
主要由妊娠引起的自身免疫性溶血性贫血(AIHA)在文献中的描述较少。关于如何应对对糖皮质激素治疗无反应的病例、监测胎儿状况以及尽早识别胎儿溶血性贫血的信息尤其匮乏。本文报告了一例妊娠诱发的自身免疫性溶血性贫血病例,该病例在鉴别诊断、治疗以及对母亲和胎儿所构成的风险方面存在重大问题。产后数周,贫血出现了自发缓解。自身免疫性溶血性贫血在文献中鲜有报道,但对胎儿和母亲都可能有危险。因此,产科医生和妇科医生应进行相关描述和讨论,并进一步研究其发病机制。