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韩国马拉色菌研究进展。

Progress in Malassezia Research in Korea.

作者信息

Kim Soo Young, Lee Yang Won, Choe Yong Beom, Ahn Kyu Joong

机构信息

Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.

出版信息

Ann Dermatol. 2015 Dec;27(6):647-57. doi: 10.5021/ad.2015.27.6.647. Epub 2015 Dec 7.

Abstract

Yeasts of the genus Malassezia are part of the normal flora of human skin. However, they are also associated with various skin diseases. Since the introduction of Malassezia to the Korean Dermatologic Society two decades ago, remarkable progress has been made in our knowledge of this genus. In this paper, we review recent developments in Malassezia research, including taxonomy and methods for species identification, recent genome analyses, Malassezia species distribution in healthy conditions and in specific skin diseases, trials investigating the mechanisms underlying Malassezia-related diseases, as well as therapeutic options. This review will enhance our understanding of Malassezia yeasts and related skin diseases in Korea.

摘要

马拉色菌属酵母是人类皮肤正常菌群的一部分。然而,它们也与多种皮肤疾病有关。自二十年前马拉色菌被引入韩国皮肤病学会以来,我们对该属的认识取得了显著进展。在本文中,我们综述了马拉色菌研究的最新进展,包括分类学和物种鉴定方法、近期的基因组分析、健康状况及特定皮肤疾病中马拉色菌的物种分布、探究马拉色菌相关疾病潜在机制的试验以及治疗选择。这篇综述将增进我们对韩国马拉色菌酵母及相关皮肤疾病的理解。

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