Eliasson A H, Moser R J, Tenholder M F
Pulmonary Disease Service, Walter Reed Army Medical Center, Washington, DC 20307-5001.
South Med J. 1989 Sep;82(9):1165-8. doi: 10.1097/00007611-198909000-00027.
Although there are several theoretic mechanisms for metastasis of ameloblastoma, hematogenous and lymphangitic spread are the most likely. Metastatic ameloblastoma in the lung can be accurately diagnosed by transbronchial biopsy. Surgical excision of metastatic ameloblastoma is one choice for treatment, but there is no good evidence that this benefits the patient. Treatment of metastatic ameloblastoma with previously used chemotherapeutic regimens has shown little clinical response and has always been followed by disease progression. There may be a role for our chemotherapy regimen for local control in dangerous locations, thereby facilitating further surgical removal and minimizing postoperative sequelae.
虽然成釉细胞瘤转移有几种理论机制，但血行转移和淋巴管转移是最可能的途径。经支气管活检可准确诊断肺内转移性成釉细胞瘤。手术切除转移性成釉细胞瘤是一种治疗选择，但没有充分证据表明这对患者有益。以往使用的化疗方案治疗转移性成釉细胞瘤临床反应甚微，且总是随之出现疾病进展。我们的化疗方案在控制危险部位的局部病灶方面可能发挥作用，从而便于进一步手术切除并将术后后遗症降至最低。
