Hyvernat P, Ollagnier C, Freidel M, Guibert B, Rochet M
Rev Mal Respir. 1985;2(1):15-8.
We report the observation of a 78 year old patient who had a plexiform ameloblastoma since the age of 38. A systematic pulmonary radiographic examination revealed multiple dense nodules like "cannon ball secondaries". However the histology of these pulmonary nodules, obtained by open lung biopsy, was identical with the primary tumour and showed no evidence of malignancy. The dispersion to the lungs was probably explained by inhalation of tumour cells, itself favoured by 8 surgical curettages. The progress of these pulmonary lesions was as slow as the primary tumour. No therapeutic trial was attempted on the grounds of age, perfect clinical tolerance and the absence of any known therapeutic protocol which would be active.
我们报告了一例78岁患者的观察情况，该患者自38岁起患有丛状成釉细胞瘤。系统性肺部放射学检查发现多个致密结节，类似“炮弹样转移瘤”。然而，通过开胸肺活检获取的这些肺结节的组织学与原发肿瘤相同，未显示恶性证据。肺部的扩散可能是由于肿瘤细胞的吸入，而8次手术刮除术促进了这种情况。这些肺部病变的进展与原发肿瘤一样缓慢。鉴于患者年龄、良好的临床耐受性以及缺乏任何已知的有效治疗方案，未尝试进行治疗试验。
