VIRALpro：一种用于识别病毒衣壳和尾部序列的工具。
VIRALpro: a tool to identify viral capsid and tail sequences.
作者信息
Galiez Clovis, Magnan Christophe N, Coste Francois, Baldi Pierre
机构信息
INRIA, Campus De Beaulieu, Rennes Cedex, 35042, France.
Department of Computer Science and Institute for Genomics and Bioinformatics, University of California, Irvine, Irvine, CA 92697, USA.
出版信息
Bioinformatics. 2016 May 1;32(9):1405-7. doi: 10.1093/bioinformatics/btv727. Epub 2016 Jan 5.
MOTIVATION
Not only sequence data continue to outpace annotation information, but also the problem is further exacerbated when organisms are underrepresented in the annotation databases. This is the case with non-human-pathogenic viruses which occur frequently in metagenomic projects. Thus, there is a need for tools capable of detecting and classifying viral sequences.
RESULTS
We describe VIRALpro a new effective tool for identifying capsid and tail protein sequences, which are the cornerstones toward viral sequence annotation and viral genome classification.
AVAILABILITY AND IMPLEMENTATION
The data, software and corresponding web server are available from http://scratch.proteomics.ics.uci.edu as part of the SCRATCH suite.
CONTACT
clovis.galiez@inria.fr or pfbaldi@uci.edu
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
动机
不仅序列数据的增长速度持续超过注释信息，而且当生物体在注释数据库中的代表性不足时，这个问题会进一步恶化。宏基因组项目中频繁出现的非人类致病病毒就是这种情况。因此，需要能够检测和分类病毒序列的工具。
结果
我们描述了VIRALpro，这是一种用于识别衣壳和尾部蛋白序列的新型有效工具，这些序列是病毒序列注释和病毒基因组分类的基石。
可用性和实现方式
数据、软件及相应的网络服务器可从http://scratch.proteomics.ics.uci.edu获取，作为SCRATCH套件的一部分。
联系方式
clovis.galiez@inria.fr或pfbaldi@uci.edu
补充信息
补充数据可在《生物信息学》在线获取。
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