急性淋巴细胞白血病治疗儿童智力发育的回顾性研究。
Retrospective study of intellectual development in children treated for acute lymphoblastic leukaemia.
作者信息
Eiser C, Lansdown R
出版信息
Arch Dis Child. 1977 Jul;52(7):525-9. doi: 10.1136/adc.52.7.525.
Abstract
Nine younger children (mean age 6-3 years) and 6 older children (mean age 9-0 years), previously treated for acute lymphoblastic leukaemia by cranial irradiation and subsequently by 2 or 3 years of chemotherapy, were assessed in terms of intellectual development in relation to 15 controls, matched individually for age, sex, and social background. All children were functioning within a normal range. The older group of children performed as well as their matched controls in all tasks. However, the younger group tended to perform somewhat below their matched controls, and this applied especially to tasks measuring quantitative, memory, and motor skills, but not to language tasks. It is concluded that there is a continual need to monitor the development of children treated for leukaemia, especially when diagnosed in the 2- to 5- year age range.
摘要
9名年幼儿童（平均年龄6.3岁）和6名年龄较大儿童（平均年龄9.0岁）曾接受过颅脑放疗治疗急性淋巴细胞白血病，随后又接受了2至3年的化疗。研究针对15名在年龄、性别和社会背景方面进行了个体匹配的对照儿童，对这些白血病患儿的智力发育情况进行了评估。所有儿童的各项功能均在正常范围内。年龄较大的那组儿童在所有任务中的表现与匹配的对照儿童相当。然而，年龄较小的那组儿童的表现往往略低于其匹配的对照儿童，这尤其体现在测量定量、记忆和运动技能的任务中，但在语言任务方面并非如此。研究得出结论，持续监测白血病治疗儿童的发育情况很有必要，尤其是那些在2至5岁年龄段被诊断出患病的儿童。
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本文引用的文献
1
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Dev Med Child Neurol. 1969 Aug;11(4):449-54. doi: 10.1111/j.1469-8749.1969.tb01463.x.
2
Psychiatric symptoms associated with L-asparaginase administration.
J Psychiatr Res. 1974 May;10(2):105-13. doi: 10.1016/0022-3956(74)90030-2.
3
Somnolence after prophylactic cranial irradiation in children with acute lymphoblastic leukaemia.急性淋巴细胞白血病患儿预防性颅脑照射后的嗜睡
Br Med J. 1973 Dec 1;4(5891):523-5. doi: 10.1136/bmj.4.5891.523.
4
Death anxiety in the outpatient leukemic child.门诊白血病患儿的死亡焦虑
Pediatrics. 1975 Dec;56(6):1035-7.
5
Effects of central-nervous-system irradiation on neuropsychologic functioning of children with acute lymphocytic leukemia.
N Engl J Med. 1975 Jul 17;293(3):113-8. doi: 10.1056/NEJM197507172930303.
6
School phobia in children with malignant neoplasms.患有恶性肿瘤儿童的学校恐惧症。
Am J Dis Child. 1975 Jan;129(1):42-6. doi: 10.1001/archpedi.1975.02120380026007.
7
Early hospital admissions and later disturbances of behaviour: an attempted replication of Douglas' findings.
Dev Med Child Neurol. 1976 Aug;18(4):447-59. doi: 10.1111/j.1469-8749.1976.tb03684.x.
8
Effects of chemotherapy on the central nervous system. A study of parenteral methotrexate in long-term survivors of leukemia and lymphoma in childhood.
Cancer. 1976 Feb;37(2 Suppl):1079-85. doi: 10.1002/1097-0142(197602)37:2+<1079::aid-cncr2820370815>3.0.co;2-d.
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