Tang Man Yee Paula, Chao Sik Yin Nicholas, Leung Wai Yip Michael, Liu Kam Wing Kelvin, Fung Po Gee Geneviere, Chan Hin Biu
*Department of Surgery, Division of Paediatric Surgery, Queen Elizabeth Hospital and United Christian Hospital †Department Of Paediatric Surgery and Adolescent Medicine, United Christian Hospital, Hong Kong.
J Craniofac Surg. 2016 Jan;27(1):29-31. doi: 10.1097/SCS.0000000000002171.
The aim of this study is to evaluate the incidence of associated congenital anomalies that is picked up by screening ultrasound of the heart, urinary system, and central nervous system (CNS) of children with cleft palate and/or lip deformities in a single regional center. A total of 225 children with cleft deformities were recruited in the study in 2009 to 2013, 91% of them underwent screening echocardiogram and of these, 98% of them were normal findings that do not require further follow-up ultrasound or treatment. Total 85% of the children underwent screening ultrasound of the urinary system and CNS, and of these, 99% were reported to have normal findings. Medium term follow-up of these children did not reveal any significant structural anomalies in the heart, brain, and urinary system that might have missed in the initial ultrasound screening. The authors suggest that in resource-limited settings, routine ultrasound screening of the heart, the CNS, and the urinary system may not be required in asymptomatic and nonsyndromic infants with cleft deformities and in those with "lip-only" cleft deformity.
本研究的目的是评估在一个单一地区中心，通过对唇腭裂患儿的心脏、泌尿系统和中枢神经系统（CNS）进行超声筛查所发现的相关先天性异常的发生率。2009年至2013年期间，共有225名有腭裂畸形的儿童被纳入该研究，其中91%接受了超声心动图筛查，其中98%的检查结果正常，无需进一步的超声随访或治疗。共有85%的儿童接受了泌尿系统和中枢神经系统的超声筛查，其中99%的检查结果报告为正常。对这些儿童的中期随访未发现心脏、大脑和泌尿系统有任何在初始超声筛查中可能遗漏的重大结构异常。作者建议，在资源有限的环境中，对于无症状、非综合征性唇腭裂婴儿以及单纯唇裂畸形婴儿，可能不需要对心脏、中枢神经系统和泌尿系统进行常规超声筛查。
