Xu Hongmei, Pi Hongying, Ma Lili, Su Xinyang, Wang Jianrong
Department of Nursing of General Hospital of Chinese People's Liberation Army, Beijing, China; Department of Nursing of Affiliated Hospital of Binzhou Medical College, Binzhou, Shandong, China.
Department of Nursing of General Hospital of Chinese People's Liberation Army, Beijing, China.
World Neurosurg. 2016 Apr;88:289-296. doi: 10.1016/j.wneu.2015.12.028. Epub 2015 Dec 30.
There have yet to be any large-scale studies in China on headaches after traumatic brain injury (TBI). We evaluate the incidence of headache after TBI and investigate risk factors and functional outcome in a large tertiary center with a high caseload.
A total of 543 patients (82% men, 18% women) with a mean age of 48.4 ± 18.6 years presenting with TBI were prospectively enrolled in this study between March 2011 and July 2013. Patient demographics, severity of TBI, incidence and classification of headache, and treatment information were collected during initial hospitalization and at 3, 6, and 12 months follow-up.
Of our 543 patients (82% men, 18% women), 62% were injured in motor vehicle collisions and 27% in falls. Most patients (97%) were considered to have mild TBI. Follow-up rates at 3, 6, and 12 months were 91%, 75%, and 61%, respectively. Only 12% of patients reported pre-TBI headaches, whereas 58% of respondents reported headache at 3 months follow-up, 54% at 6 months follow-up, and 49% at 1 year follow-up. No statistically significant correlations between age, sex, or TBI severity and posttraumatic headaches were observed.
We present the findings of the first study on headaches after TBI in China. Headaches were found to occur in most patients with TBI and persisted through the first year after injury. The incidence of posttraumatic headache observed here is comparable with previously published studies outside China.
中国尚未有关于创伤性脑损伤（TBI）后头痛的大规模研究。我们在一个病例数量众多的大型三级中心评估TBI后头痛的发生率，并调查危险因素及功能结局。
2011年3月至2013年7月期间，前瞻性纳入了共543例TBI患者（男性占82%，女性占18%），平均年龄为48.4±18.6岁。在初次住院期间以及随访3个月、6个月和12个月时收集患者的人口统计学信息、TBI严重程度、头痛的发生率和分类以及治疗信息。
在我们的543例患者中（男性占82%，女性占18%），62%因机动车碰撞受伤，27%因跌倒受伤。大多数患者（97%）被认为是轻度TBI。3个月、6个月和12个月时的随访率分别为91%、75%和61%。只有12%的患者报告TBI前有头痛，而在随访3个月时58%的受访者报告有头痛，6个月时为54%，1年时为49%。未观察到年龄、性别或TBI严重程度与创伤后头痛之间存在统计学上的显著相关性。
我们展示了中国第一项关于TBI后头痛的研究结果。发现大多数TBI患者会出现头痛，且在受伤后的第一年持续存在。这里观察到的创伤后头痛发生率与中国以外先前发表的研究相当。
