Beuscart C, Leroy O, Mouton Y, Pappo M, Drugeon H
Service Régional des Maladies Infectieuses, Centre Hospitalier de Tourcoing.
Pathol Biol (Paris). 1989 May;37(5):496-9.
Three hundred fifty-two patients from 20 intensive care units, suffering from pneumonia or nosocomial septicemia were treated at random with either ceftazidime + pefloxacin (CP) or ceftazidime + amikacin (CA). After exclusion of patients who did not comply with the protocol and of cases where no organism was isolated, 108 assessable patients received CP and 114 received CA. The cure rates achieved in infections due to a single organism were 82 per cent in the CA group and 62 per cent in the CP group. In infections due to multiple organisms, the cure rate was 67 per cent with both antibiotic regimens.
来自20个重症监护病房的352例患有肺炎或医院败血症的患者被随机分为两组，分别接受头孢他啶+培氟沙星（CP）或头孢他啶+阿米卡星（CA）治疗。在排除不符合方案的患者以及未分离出病原体的病例后，108例可评估患者接受了CP治疗，114例接受了CA治疗。单种病原体感染的治愈率在CA组为82%，在CP组为62%。在多种病原体感染中，两种抗生素治疗方案的治愈率均为67%。
