Abu Samra Khawla, Maghsoudlou Armin, Roohipoor Ramak, Valdes-Navarro Manuel, Lee Stacey, Foster C Stephen
a Massachusetts Eye Research and Surgery Institution (MERSI) , Waltham , Massachusetts , USA.
b Ocular Immunology and Uveitis Foundation (OIUF) , Waltham , Massachusetts , USA.
Ocul Immunol Inflamm. 2016 Aug;24(4):431-9. doi: 10.3109/09273948.2015.1115878. Epub 2016 Jan 14.
Uveitis is a common and serious complication of juvenile idiopathic arthritis. Up to 75% of all cases of anterior uveitis in childhood are associated with juvenile idiopathic arthritis. Despite the remarkable progress in early detection and treatment of inflammation, vision-threatening complications of uveitis still occur in almost 60% of patients. Structural complications include band keratopathy, maculopathy (macular edema, macular cysts, and epiretinal membrane), glaucomatous optic neuropathy, and cataracts. The management of complications in juvenile idiopathic arthritis is usually complex and requires early surgical intervention. In this paper, we review the general concepts of common ocular complications seen in patients with JIA-associated uveitis, with special attention to the recent diagnostic and preferred treatment approaches at the Massachusetts Eye Research and Surgery Institution. Received 9 March 2015; revised 30 September 2015; accepted 30 October 2015; published online 14 January 2016.
葡萄膜炎是幼年特发性关节炎常见且严重的并发症。儿童期所有前葡萄膜炎病例中，高达75%与幼年特发性关节炎相关。尽管在炎症的早期检测和治疗方面取得了显著进展，但葡萄膜炎仍会在近60%的患者中引发威胁视力的并发症。结构并发症包括带状角膜病变、黄斑病变（黄斑水肿、黄斑囊肿和视网膜前膜）、青光眼性视神经病变和白内障。幼年特发性关节炎并发症的管理通常较为复杂，需要早期手术干预。在本文中，我们回顾了幼年特发性关节炎相关葡萄膜炎患者常见眼部并发症的一般概念，特别关注马萨诸塞州眼研究与手术机构最近的诊断和首选治疗方法。2015年3月9日收到；2015年9月30日修订；2015年10月30日接受；2016年1月14日在线发表。
