Department of Ophthalmology, Niigata University Medical and Dental Hospital, Niigata, Japan.
J Glaucoma. 2014 Feb;23(2):81-7. doi: 10.1097/IJG.0b013e318265bbdc.
To investigate the significance of vision-specific quality of life (QOL) in glaucoma patients based on the location of visual field defects.
We examined 336 eyes of 168 patients. The 25-item National Eye Institute Visual Function Questionnaire was used to evaluate patients' QOL. Visual field testing was performed using the Humphrey Field Analyzer; the visual field was divided into 10 clusters. We defined the eye with better mean deviation as the better eye and the fellow eye as the worse eye. A single linear regression analysis was applied to assess the significance of the relationship between QOL and the clustered visual field.
The strongest correlation was observed in the lower paracentral visual field in the better eye. The lower peripheral visual field in the better eye also showed a good correlation. Correlation coefficients in the better eye were generally higher than those in the worse eye. For driving, the upper temporal visual field in the better eye was the most strongly correlated (r=0.509). For role limitation and peripheral vision, the lower peripheral visual field in the better eye had the highest correlation coefficients at 0.459 and 0.425, respectively.
Overall, clusters in the lower hemifield in the better eye were more strongly correlated with QOL than those in the worse eye. In particular, the lower paracentral visual field in the better eye was correlated most strongly of all. Driving, however, strongly correlated with the upper hemifield in the better eye.
基于视野缺损位置，探讨青光眼患者视功能特定生活质量（QOL）的意义。
我们检查了 168 例患者的 336 只眼。采用 25 项国家眼科研究所视觉功能问卷评估患者的 QOL。使用 Humphrey 视野分析仪进行视野检查；将视野分为 10 个簇。我们将平均偏差较好的眼定义为优势眼，对侧眼为劣势眼。采用单一线性回归分析评估 QOL 与簇状视野之间关系的显著性。
在优势眼的下旁中心视野中观察到最强的相关性。在优势眼的下周边视野也显示出良好的相关性。优势眼的相关系数通常高于劣势眼。对于驾驶，优势眼的上颞侧视野相关性最强（r=0.509）。对于角色限制和周边视力，优势眼的下周边视野的相关系数最高，分别为 0.459 和 0.425。
总体而言，优势眼的下半视野簇与 QOL 的相关性强于劣势眼。特别是，优势眼的下旁中心视野相关性最强。然而，驾驶与优势眼的上半视野强烈相关。
