Sul Hye Ryoung, Lee Hyun Woong, Kim Jeong Wook, Cha Sung Jae, Choi Yoo Shin, Kim Gi Hyeon, Kwak Byung Kook
Department of Internal Medicine, Chung-Ang University College of Medicine, 224-1 Heuk Seok-Dong, Dongjak-Ku, Seoul, 156-755, Republic of Korea.
Department of Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
BMC Gastroenterol. 2016 Jan 14;16:5. doi: 10.1186/s12876-016-0418-3.
Hemorrhage from the pancreatic duct, or hemosuccus pancreaticus (HP), is an unusual cause of intermittent gastrointestinal bleeding. HP is most often diagnosed in patients with chronic pancreatitis, and is usually due to the rupture of an aneurysm in the splenic artery. The traditional treatment for HP is surgery, although most cases can be managed by angioembolization.
We present a case of HP in a patient with no history or evidence of chronic pancreatitis. Repeated endoscopy revealed fresh bleeding from the papilla of Vater. Angiography revealed an aneurysm of the splenic artery, which was the suspected cause of the intermittent bleeding from the pancreatic duct. Angiography demonstrated extravasation of contrast from the aneurysm. A peripheral Jostent stent-graft was hand-mounted on an angioplasty balloon and then inserted into the aneurysm. Arteriography revealed successful occlusion of the aneurysm with the stent-graft. No recurrent gastrointestinal bleeding was observed during the five years follow-up periods.
HP should be included in the differential diagnosis of intermittent gastrointestinal bleeding in patients with histories of chronic alcoholism, even when they do not have a history of chronic pancreatitis. We recommend an interventional procedure with a metal stent for the initial treatment of HP.
胰管出血,即胰源性门脉高压(HP),是间歇性胃肠道出血的一种罕见原因。HP最常诊断于慢性胰腺炎患者中,通常是由于脾动脉动脉瘤破裂所致。HP的传统治疗方法是手术,尽管大多数病例可通过血管栓塞治疗。
我们报告一例无慢性胰腺炎病史或证据的HP患者。反复内镜检查显示来自十二指肠乳头的新鲜出血。血管造影显示脾动脉有一个动脉瘤,怀疑是胰管间歇性出血的原因。血管造影显示造影剂从动脉瘤外渗。将一个外周Jostent支架移植物手工安装在血管成形球囊上,然后插入动脉瘤。动脉造影显示支架移植物成功闭塞动脉瘤。在五年随访期间未观察到复发性胃肠道出血。
即使没有慢性胰腺炎病史,HP也应纳入慢性酒精中毒患者间歇性胃肠道出血的鉴别诊断中。我们建议采用金属支架介入治疗作为HP的初始治疗方法。