Karaman Serap, Karaman Kamuran, Kızılyıldız Baran Serdar, Ceylan Nesrin, Kaba Sultan, Parlak Mehmet, Beger Burhan, Ceylan Abdullah
Department of Pediatrics and Pediatric Surgery, Faculty of Medicine, Yüzüncü Yıl University Van, Turkey.
Department of Pediatrics, Private Istanbul Hospital Van, Turkey.
Int J Clin Exp Med. 2015 Oct 15;8(10):19394-9. eCollection 2015.
Hepatitis A is a common infectious disease during childhood worldwide. Recently, great deal of changes in the epidemiology has been reported. The seroepidemiologic studies of this infection are not sufficient in Eastern region of Turkey.
To investigate the seroprevalence and association with socio-demographic variables of hepatitis A in 1-15 year old children in Van.
This study was performed on 510 one to fifteen year old children from outpatient pediatric clinics in Yüzüncü Yıl University, Faculty of Medicine during last three months of 2009. Anti-HAV IgG was measured in sera by enzyme-linked immunosorbent assay. The information about subjects was recorded on standardized forms and a chart review survey was performed.
The overall ratio for seropositivity was 54.9%. Statistical significance was found between hepatitis A seroprevalence and age, collective use of domestic items, fresh water resources, localization and type of toilet and the number of households.
This study provided the most recent data of seropositivity and revealed the preliminary indication of epidemiological shift in seroprevalence of Hepatitis A virus in a region with high endemicity.
甲型肝炎是全球儿童期常见的传染病。最近，有报道称其流行病学发生了很大变化。在土耳其东部地区，关于这种感染的血清流行病学研究并不充分。
调查凡城1至15岁儿童甲型肝炎的血清流行率及其与社会人口统计学变量的关系。
本研究于2009年最后三个月对来自于约兹加特医科大学医学院门诊儿科诊所的510名1至15岁儿童进行。采用酶联免疫吸附测定法检测血清中的抗甲型肝炎病毒IgG。有关受试者的信息记录在标准化表格上，并进行图表回顾调查。
血清阳性的总体比例为54.9%。发现甲型肝炎血清流行率与年龄、家庭用品的集体使用情况、淡水资源、厕所的位置和类型以及家庭数量之间存在统计学意义。
本研究提供了血清阳性的最新数据，并揭示了高流行地区甲型肝炎病毒血清流行率流行病学转变的初步迹象。
