一例伴有七种副肿瘤综合征的罕见胸腺瘤病例。
A rare thymoma case with seven paraneoplastic syndromes.
作者信息
Gong Li, Zhang Pei, Liu Xue-Yuan, Fang Min
机构信息
Department of Neurology, Shanghai Tenth People Hospital, Tongji University, School of Medicine China.
出版信息
Int J Clin Exp Med. 2015 Oct 15;8(10):19517-23. eCollection 2015.
Abstract
Thymoma is a kind of epithelial tumor of the thymus which about 30-50% patients accompanied by paraneoplastic disorders. However, the coexistence of seven symptoms in an individual is rare. This report represented a patient, diagnosed of thymoma, with myasthenia gravis, erythema multiforme, plasma cell cheilitis, recurrent oral ulcer, vitiligo, Raynaud's phenomenon and fissured tongue. Detailed clinical manifestations, serum immune biomarkers, imaging study, electrophysiology examination and pathology results are described in this case.
摘要
胸腺瘤是一种胸腺上皮肿瘤，约30%-50%的患者伴有副肿瘤综合征。然而，个体同时出现七种症状的情况较为罕见。本报告介绍了一名被诊断为胸腺瘤的患者，其同时患有重症肌无力、多形红斑、浆细胞性唇炎、复发性口腔溃疡、白癜风、雷诺现象和沟纹舌。本病例描述了详细的临床表现、血清免疫生物标志物、影像学检查、电生理检查及病理结果。
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