Janečka Jan, Lysak Martin A
CEITEC-Central European Institute of Technology, Masaryk University, Kamenice 5, Brno, 62500, Czech Republic.
Chromosome Res. 2016 May;24(2):217-23. doi: 10.1007/s10577-015-9513-5. Epub 2016 Jan 20.
Species-specific sets of chromosomes-karyotypes-are traditionally depicted as linear ideograms with individual chromosomes represented by vertical bars. However, linear visualization has its limitations when the shared collinearity and/or chromosomal rearrangements differentiating two or more karyotypes need to be demonstrated. In these instances, circular visualization might provide easier comprehension and interpretation of inter-species chromosomal collinearity. The chromDraw graphical tool was developed as a user-friendly graphical tool for visualizing both linear and circular karyotypes based on the same input data matrix. The output graphics, saved in two different formats (EPS and SVG), can be easily imported to and modified in presentation and image-editing computer programs. The tool is freely distributed under GNU General Public License (GPL) and can be installed from Bioconductor or from the chromDraw home page.
特定物种的染色体组——核型——传统上被描绘为线性模式图，其中每条染色体由垂直条表示。然而，当需要展示区分两个或更多核型的共享共线性和/或染色体重排时，线性可视化存在局限性。在这些情况下，圆形可视化可能会使种间染色体共线性更容易理解和解释。chromDraw图形工具是作为一种用户友好的图形工具开发的，用于基于相同的输入数据矩阵可视化线性和圆形核型。以两种不同格式（EPS和SVG）保存的输出图形可以轻松导入到演示文稿和图像编辑计算机程序中并进行修改。该工具根据GNU通用公共许可证（GPL）免费分发，可以从Bioconductor或chromDraw主页安装。
