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GeMo:一个用于可视化和管理基因组祖先镶嵌体的基于网络的平台。

GeMo: a web-based platform for the visualization and curation of genome ancestry mosaics.

机构信息

CIRAD, UMR AGAP Institut, Montpellier 34398, France.

UMR AGAP Institut, Univ Montpellier, CIRAD, INRAE, Institut Agro, Montpellier, 34398, France.

出版信息

Database (Oxford). 2022 Jul 14;2022. doi: 10.1093/database/baac057.

Abstract

In silico chromosome painting is a technique by which contributions of distinct genetic groups are represented along chromosomes of hybrid individuals. This type of analysis is used to study the mechanisms by which these individuals were formed. Such techniques are well adapted to identify genetic groups contributing to these individuals as well as hybridization events. It can also be used to follow chromosomal recombinations that occurred naturally or were generated by selective breeding. Here, we present GeMo, a novel interactive web-based and user-oriented interface to visualize in a linear-based fashion results of in silico chromosome painting. To facilitate data input generation, a script to execute analytical commands is provided and an interactive data curation mode is supported to ensure consistency of the automated procedure. GeMo contains preloaded datasets from published studies on crop domestication but can be applied to other purposes, such as breeding programs Although only applied so far on plants, GeMo can handle data from animals as well. Database URL: https://gemo.southgreen.fr/.

摘要

计算机染色体作图是一种技术,通过该技术可以在杂种个体的染色体上表示不同遗传群体的贡献。这种分析类型用于研究这些个体形成的机制。此类技术非常适合识别为这些个体做出贡献的遗传群体以及杂交事件。它还可用于跟踪自然发生或通过选择性繁殖产生的染色体重组。在这里,我们介绍了 GeMo,这是一种新颖的基于网络的交互式用户导向界面,用于以基于线性的方式可视化计算机染色体作图的结果。为了方便生成数据输入,提供了一个脚本来执行分析命令,并支持交互式数据管理模式,以确保自动过程的一致性。GeMo 包含来自作物驯化发表研究的预加载数据集,但也可用于其他目的,例如繁殖计划。尽管迄今为止仅在植物上应用,但 GeMo 也可以处理来自动物的数据。数据库 URL:https://gemo.southgreen.fr/。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26f6/9290862/02a3ff1a9780/baac057f1.jpg

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