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手足口病

Mouth in Foot Disease.

作者信息

Melton Katie S, DeRosa Daniel C, Agee Willie A, Pires Valerie L, Yim Duke G, Ngauy Viseth

机构信息

Department of Medicine, Tripler Army Medical Center, Honolulu HI (KSM, VLP).

出版信息

Hawaii J Med Public Health. 2015 Sep;74(9 Suppl 2):30-2.

Abstract

Toothpicks are commonly used household items that rarely cause serious injury or infection. Toothpick-related injuries often occur due to ingestion with subsequent trauma/infection at distal sites within the gastrointestinal tract; however, cardiovascular, pleural, and soft tissue infections have been reported. Eikenella corrodens is a gram-negative, facultative anaerobic bacillus found in oral flora associated with bite wound infections. A few case reports describe E. corrodens osteomyelitis from toothpick puncture wounds. We report a case of foot cellulitis and abscess in an elderly diabetic after toothpick puncture injury that was unresponsive to empiric antibiotics. Wound cultures grew E. corrodens and rare Peptostreptococcus species. E. corrodens is resistant to first-generation cephalosporins, macrolides, aminoglycosides, clindamycin, and metronidazole. This case highlights the insidious nature of E. corrodens infections and the need to tailor empiric antibiotics for skin and soft tissue infections based on the mechanism of injury. In addition, this case stresses the importance of protective footwear in diabetics and serves as a cautionary tale regarding the use of seemingly innocuous toothpicks.

摘要

牙签是常用的家居用品,很少会造成严重损伤或感染。与牙签相关的损伤通常是由于误食,随后在胃肠道远端部位发生创伤/感染;不过,也有心血管、胸膜和软组织感染的报道。腐蚀埃肯菌是一种革兰氏阴性兼性厌氧杆菌,存在于与咬伤伤口感染相关的口腔菌群中。有几例病例报告描述了因牙签刺伤导致的腐蚀埃肯菌骨髓炎。我们报告一例老年糖尿病患者在牙签刺伤后发生足部蜂窝织炎和脓肿,经验性使用抗生素治疗无效。伤口培养物中生长出腐蚀埃肯菌和罕见的消化链球菌属菌种。腐蚀埃肯菌对第一代头孢菌素、大环内酯类、氨基糖苷类、克林霉素和甲硝唑耐药。本病例突出了腐蚀埃肯菌感染的隐匿性,以及根据损伤机制调整皮肤和软组织感染经验性抗生素使用的必要性。此外,本病例强调了糖尿病患者穿防护鞋的重要性,并警示人们看似无害的牙签的使用风险。

相似文献

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Mouth in Foot Disease.
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本文引用的文献

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Treatment of Eikenella corrodens and Actinomyces odontolyticus foot abscess in a penicillin-allergic patient.
Ann Pharmacother. 2008 Nov;42(11):1706-10. doi: 10.1345/aph.1L257. Epub 2008 Oct 14.
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