Soy Fatih Kemal, Yazıcı Haşmet, Kulduk Erkan, Dündar Rıza, Gülen Şule Taş, Doğan Sedat, Can İlknur Haberal
Department of Otolaryngology, Mardin State Hospital, 47200 Mardin, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2016;26(1):19-27. doi: 10.5606/kbbihtisas.2016.56254.
This study aims to investigate the quality of life of allergic patients with or without asthma during dust storms.
A total of 148 allergic patients (66 males, 82 females; mean age 35.7±15.5 years; range 18 to 65 years) were classified as those with (group 1, n=80) or without (group 2, n=68) concomitant asthma between January 2012 and January 2013. The quality of life [Short Form-36 (SF-36)] scores, Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ), nasal symptom and visual analog scale (VAS) scores at the time of diagnosis were obtained. The particulate matter (PM10) and sulfur dioxide (SO2) values of that day from the General Directorate of Meteorology were recorded. The day of dust storm and PM10 and SO2 measurements along with SF-36, RQLQ, nasal symptom and VAS scores were recorded again.
The absolute change in the RQLQ subparameters including eye and nasal symptoms, practical problems and global scores was statistically significant (p=0.022, p=0.036, p=0.026 and p=0.032, respectively). There were statistically significant changes in the SF-36 subgroups of general health, physical functioning, vitality, and mental health (p=0.026, p=0.042, p=0.008 and p=0.026, respectively). In the multivariate logistic regression model, specific and general quality of life was 4.6 times worse in RQLQ and 3.8 times in SF-36 after the dust storm in patients with asthma, while 2.1 times worse in RQLQ and 1.9 times in SF-36 in patients with pure allergic rhinitis. The attributable risk of asthma was found to be 2.5 times higher in RQLQ and 1.9 times higher in SF-36.
Dust storms may deteriorate the quality of life of patients with allergic rhinitis and asthma and lead to related personal and societal problems.
本研究旨在调查沙尘暴期间有或无哮喘的过敏患者的生活质量。
2012年1月至2013年1月期间，共有148例过敏患者（66例男性，82例女性；平均年龄35.7±15.5岁；年龄范围18至65岁）被分为伴有哮喘（第1组，n = 80）或不伴有哮喘（第2组，n = 68）。获取诊断时的生活质量[简明健康状况调查量表（SF - 36）]得分、鼻结膜炎生活质量问卷（RQLQ）、鼻部症状及视觉模拟量表（VAS）得分。记录当天气象总局的颗粒物（PM10）和二氧化硫（SO2）值。再次记录沙尘暴当天以及PM10和SO2测量值，同时记录SF - 36、RQLQ、鼻部症状及VAS得分。
RQLQ子参数（包括眼部和鼻部症状、实际问题及总体得分）的绝对变化具有统计学意义（分别为p = 0.022、p = 0.036、p = 0.026和p = 0.032）。SF - 36亚组中的一般健康、身体功能、活力及心理健康方面有统计学意义的变化（分别为p = 0.026、p = 0.042、p = 0.008和p = 0.026）。在多因素逻辑回归模型中，哮喘患者在沙尘暴后RQLQ中特定和总体生活质量恶化4.6倍，SF - 36中恶化3.8倍；而单纯过敏性鼻炎患者在RQLQ中恶化2.1倍，SF - 36中恶化1.9倍。发现哮喘在RQLQ中的归因风险高2.5倍，在SF - 36中高1.9倍。
沙尘暴可能会使过敏性鼻炎和哮喘患者的生活质量恶化，并导致相关的个人和社会问题。
