Laugisch Oliver, Ramseier Christoph A, Salvi Giovanni E, Hägi Tobias T, Bürgin Walter, Eick Sigrun, Sculean Anton
Department of Periodontology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, 3010, Bern, Switzerland.
School of Dental Medicine, University of Bern, Bern, Switzerland.
Clin Oral Investig. 2016 Nov;20(8):2175-2183. doi: 10.1007/s00784-016-1713-7. Epub 2016 Jan 22.
The aim of this study was to compare early wound healing, tooth staining and patient acceptance with two different post-surgical maintenance protocols.
Forty patients scheduled for flap surgery to treat periodontal pockets or accommodate dental implants were randomly assigned to receive the following two different post-surgical maintenance protocols: (a) 2 weeks rinsing with a 0.05 % chlorhexidine digluconate (CHX)/herbal extract combination (test) or (b) a 0.1 % CHX solution (control). Early wound healing was evaluated clinically and immunologically. Tooth staining and patient acceptance were assessed by means of visual analogue scale (VAS).
Both groups presented with comparable wound healing profiles. No statistically significant differences were observed between the two protocols regarding early wound healing and plaque index (p > 0.05). However, in the control group, statistically significantly more patients felt discomfort due to tooth staining (p = 0.0467). Compared with patients from the test group, patients in the control group reported statistically significant more irritation of taste at week 1 (p = 0.0359) and at week 2 (p = 0.0042).
The present findings indicate that the two CHX protocols resulted in comparable healing and inhibition of plaque formation. Tooth staining and subjective discomfort related to irritation of taste were more frequent in the control group.
A post-operative protocol including 0.05 % CHX/herbal extract may have the potential to improve patient compliance during post-operative maintenance.
本研究旨在比较两种不同的术后维护方案在早期伤口愈合、牙齿染色及患者接受度方面的情况。
40例计划接受翻瓣手术治疗牙周袋或植入牙种植体的患者被随机分配接受以下两种不同的术后维护方案:(a)用0.05%葡萄糖酸洗必泰(CHX)/草药提取物组合冲洗2周(试验组)或(b)0.1%CHX溶液(对照组)。通过临床和免疫学方法评估早期伤口愈合情况。采用视觉模拟量表(VAS)评估牙齿染色和患者接受度。
两组的伤口愈合情况相当。两种方案在早期伤口愈合和菌斑指数方面未观察到统计学上的显著差异(p>0.05)。然而,在对照组中,因牙齿染色而感到不适的患者在统计学上显著更多(p=0.0467)。与试验组患者相比,对照组患者在第1周(p=0.0359)和第2周(p=0.0042)报告味觉刺激的情况在统计学上显著更多。
目前的研究结果表明,两种CHX方案在愈合和抑制菌斑形成方面效果相当。对照组中牙齿染色和与味觉刺激相关的主观不适更为常见。
包含0.05%CHX/草药提取物的术后方案可能有潜力提高术后维护期间患者的依从性。