健康土耳其儿童的规范性光谱域光学相干断层扫描数据
Normative Spectral Domain Optical Coherence Tomography Data in Healthy Turkish Children.
作者信息
Gürağaç Fatma Betül, Totan Yüksel, Güler Emre, Tenlik Aylin, Ertuğrul İhsan Gökhan
机构信息
a Gölbaşı Hasvak State Hospital, Eye Clinic , Ankara , Turkey.
b Turgut Özal University, Medical School, Department of Ophthalmology , Ankara , Turkey , and.
出版信息
Semin Ophthalmol. 2017;32(2):216-222. doi: 10.3109/08820538.2015.1053625. Epub 2016 Jan 21.
PURPOSE
To determine the normative database of macular and retinal nerve fiber layer (RNFL) thickness parameters in healthy Turkish children by OCT.
METHODS
318 eyes of 318 children (138 boys, 183 girls) aged between 3 and 17 years were evaluated. The children were scanned by Cirrus HD-OCT (Carl Zeiss Meditec) to measure the macula, RNFL, and optic nerve head parameters.
RESULTS
Axial length (AL) (p < 0.001, R= 0.08), spherical equivalent (SE) (p < 0.001, R= 0.12), and rim area (p < 0.001, R= 0.15) were the strongest predictors of RNFL thickness. All of the macular measurements were significantly related to age (p < 0.001, R> 5%). Average macular thickness (p < 0.01) and outer macula (p = 0.002) showed significant relationship with the AL and SE.
CONCLUSION
This study ensures an age-adjusted pediatric normative database using OCT to diagnose and monitor macular diseases, optic nerve diseases, and glaucoma in children.
目的
通过光学相干断层扫描（OCT）确定健康土耳其儿童黄斑和视网膜神经纤维层（RNFL）厚度参数的标准数据库。
方法
对318名年龄在3至17岁之间的儿童（138名男孩，183名女孩）的318只眼睛进行评估。使用Cirrus HD-OCT（卡尔蔡司医疗技术公司）对儿童进行扫描，以测量黄斑、RNFL和视神经乳头参数。
结果
眼轴长度（AL）（p < 0.001，R = 0.08）、等效球镜度（SE）（p < 0.001，R = 0.12）和视盘边缘面积（p < 0.001，R = 0.15）是RNFL厚度的最强预测因素。所有黄斑测量值均与年龄显著相关（p < 0.001，R > 5%）。平均黄斑厚度（p < 0.01）和黄斑外层（p = 0.002）与AL和SE显示出显著关系。
结论
本研究利用OCT建立了一个年龄校正的儿科标准数据库，用于诊断和监测儿童黄斑疾病、视神经疾病和青光眼。
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