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作为复杂、大型且部分血栓形成的颅内动脉瘤多模态治疗一部分的WEB:一项关于技术成功率、安全性和复发率的单中心观察性研究

WEB as part of a multimodality treatment in complex, large, and partially thrombosed intracranial aneurysms: a single-center observational study of technical success, safety, and recurrence.

作者信息

Kabbasch C, Mpotsaris A, Reiner M, Liebig T

机构信息

Department of Radiology and Neuroradiology, University Hospital of Cologne, Cologne, Germany.

Department of Neurosurgery, University Hospital of Cologne, Cologne, Germany.

出版信息

J Neurointerv Surg. 2016 Dec;8(12):1235-1239. doi: 10.1136/neurintsurg-2015-012126. Epub 2016 Jan 22.

Abstract

INTRODUCTION

Complex, large, wide-neck aneurysms, but particularly partially thrombosed intracranial aneurysms (PTIAs), have a greater tendency to recanalize after coil occlusion. The Woven Endovascular Bridge (WEB) combines shape memory wires braided to a relatively uniform, dense surface, which may limit its compaction and its incorporation into an existing aneurysm clot and may thus reduce PTIA recurrence.

OBJECTIVE

To carry out a retrospective analysis of our experience with the WEB as part of a complex treatment in conjunction with other implants to assess the efficacy and safety of this technique.

METHODS

Among 43 aneurysms treated with the WEB in our center, eight complex, large, wide-neck aneurysms were treated in conjunction with other implants (additional WEBs, coils, stents, flow diverters). Six of these eight aneurysms were PTIAs. All patients were followed up by DSA between 3½ and 38 months.

RESULTS

All eight (100%) of the complex, large, wide-neck aneurysms were treated successfully and without periprocedural adverse events (0%). At follow-up, the two non-thrombosed aneurysms were completely occluded, but all six PTIAs recurred (75%) and were re-treated. There was no morbidity or mortality in these eight patients.

CONCLUSIONS

Treatment of large, complex aneurysms with the WEB in conjunction with other implants was technically successful and safe but did not prevent recurrence of partially thrombosed aneurysms in our center. PTIA re-treatment was possible and not limited by the previously placed WEB.

摘要

引言

复杂、大型、宽颈动脉瘤,尤其是部分血栓形成的颅内动脉瘤(PTIA),在弹簧圈栓塞后有更大的再通倾向。编织型血管内桥接器(WEB)由编织成相对均匀、致密表面的形状记忆金属丝组成,这可能会限制其压实以及与现有动脉瘤血栓的融合,从而可能降低PTIA的复发率。

目的

对我们使用WEB作为联合其他植入物的复杂治疗一部分的经验进行回顾性分析,以评估该技术的有效性和安全性。

方法

在我们中心接受WEB治疗的43个动脉瘤中,8个复杂、大型、宽颈动脉瘤联合其他植入物(额外的WEB、弹簧圈、支架、血流导向装置)进行了治疗。这8个动脉瘤中有6个是PTIA。所有患者在3个半月至38个月之间接受了数字减影血管造影(DSA)随访。

结果

所有8个(100%)复杂、大型、宽颈动脉瘤均成功治疗,且围手术期无不良事件发生(0%)。随访时,2个未血栓形成的动脉瘤完全闭塞,但所有6个PTIA均复发(75%)并接受了再次治疗。这8例患者均无 morbidity 或 mortality。

结论

在我们中心,使用WEB联合其他植入物治疗大型、复杂动脉瘤在技术上是成功且安全的,但未能预防部分血栓形成动脉瘤的复发。PTIA再次治疗是可行的,且不受先前放置的WEB限制。

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