Squillace Lorenzo, Cappello Milena, Longo Caterina, Moscarella Elvira, Alfano Roberto, Argenziano Giuseppe
Dermatology Unit, Second University of Naples, Naples, Italy.
Dermatology. 2016;232(2):198-202. doi: 10.1159/000442439. Epub 2016 Jan 27.
Seborrheic keratoses (SKs) may sometimes mimic benign and malignant skin tumors, and a biopsy can be necessary in order to rule out malignancy.
From the database of our pigmented lesion clinic, we evaluated the dermoscopic features of difficult-to-diagnose SKs that were biopsied between January 2010 and December 2014.
SKs represented 3.8% of all excised lesions (161/ 4,182). Specifically, 91 (56.5%) were excised to rule out melanoma, 63 (39.1%) to rule out squamous cell carcinoma and 7 (4.4%) to rule out basal cell carcinoma. The following 10 global dermoscopic patterns were identified: multicomponent (32; 19.9%); reticular (24; 14.9%), characterized by an irregular pigment network; bowenoid (21; 13.0%); hairpin (19; 11.8%); keratoacanthoma-like (16; 9.9%); blue-nevus-like (15; 9.3%); lichenoid (6; 3.7%); hyperkeratotic (6; 3.7%); clonal (5; 3.1%); spitzoid (5; 3.1%). Furthermore, 12 SKs (7.5%) were not included in any of such patterns (not classified).
Our results are in line with previous studies highlighting the dermoscopic variability of SKs. Although excised SKs may be classified into 1 of 10 repetitive dermoscopic patterns, a biopsy remains mandatory for those that cannot be clearly differentiated from common skin malignancies.
脂溢性角化病(SKs)有时可能会与良性和恶性皮肤肿瘤相似,因此可能需要进行活检以排除恶性肿瘤。
从我们色素沉着病变诊所的数据库中,我们评估了2010年1月至2014年12月间接受活检的难以诊断的SKs的皮肤镜特征。
SKs占所有切除病变的3.8%(161/4182)。具体而言,91例(56.5%)切除是为了排除黑色素瘤,63例(39.1%)是为了排除鳞状细胞癌,7例(4.4%)是为了排除基底细胞癌。确定了以下10种整体皮肤镜模式:多成分型(32例;19.9%);网状型(24例;14.9%),其特征为不规则色素网;鲍温样型(21例;13.0%);发夹型(19例;11.8%);角化棘皮瘤样型(16例;9.9%);蓝痣样型(15例;9.3%);苔藓样型(6例;3.7%);角化过度型(6例;3.7%);克隆型(5例;3.1%);斯皮茨样型(5例;3.1%)。此外,12例SKs(7.5%)未包含在任何此类模式中(未分类)。
我们的结果与之前强调SKs皮肤镜表现多变性的研究一致。尽管切除的SKs可分为10种重复性皮肤镜模式中的一种,但对于那些无法与常见皮肤恶性肿瘤明确区分的病变,活检仍然是必要的。