Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Pathol Oncol Res. 2023 Jun 12;29:1611204. doi: 10.3389/pore.2023.1611204. eCollection 2023.
Tumor-to-tumor metastasis is a rare phenomenon. Although renal cell carcinoma is the most common recipient tumor, metastatic lobular breast carcinoma to clear cell renal cell carcinoma is even rarer, with only one case reported to date. We present a 66-year-old female patient with an invasive lobular carcinoma history who was admitted to the hospital with a right renal mass. The patient received partial nephrectomy. The final established diagnosis is lobular breast carcinoma metastasizing to clear cell renal cell carcinoma (ccRCC). Thus, although rare, the simultaneous or consecutive find of a renal mass in follow-up should be carefully evaluated, especially in high-risk patients, including women with an advanced breast cancer history, as in this scenario.
肿瘤对肿瘤转移是一种罕见现象。虽然肾细胞癌是最常见的受肿瘤，但转移的乳腺浸润性小叶癌至透明细胞肾细胞癌更为罕见，迄今为止仅报告过一例。我们报告了一位 66 岁女性患者，她有浸润性小叶癌病史，因右肾肿块住院。患者接受了部分肾切除术。最终确立的诊断是乳腺浸润性小叶癌转移至透明细胞肾细胞癌（ccRCC）。因此，尽管罕见，但在随访中发现同时或连续出现肾肿块时应仔细评估，特别是在高危患者中，包括有晚期乳腺癌病史的女性，就像本例中一样。
