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Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.

作者信息

Padlan E A, Davies D R, Pecht I, Givol D, Wright C

出版信息

Cold Spring Harb Symp Quant Biol. 1977;41 Pt 2:627-37. doi: 10.1101/sqb.1977.041.01.072.

DOI:10.1101/sqb.1977.041.01.072
PMID:268248
Abstract
摘要

相似文献

1
Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.抗原结合位点的模型构建研究：Mopc-315的半抗原结合位点
Cold Spring Harb Symp Quant Biol. 1977;41 Pt 2:627-37. doi: 10.1101/sqb.1977.041.01.072.
2
Resonance Raman-spectroscopic studies of the hapten features involved in the binding of 2,4-dinitrophenyl haptens by the mouse myeloma proteins MOPC 315 and MOPC 460.对小鼠骨髓瘤蛋白MOPC 315和MOPC 460与2,4-二硝基苯基半抗原结合所涉及的半抗原特征进行共振拉曼光谱研究。
Biochem J. 1978 Nov 1;175(2):727-35. doi: 10.1042/bj1750727.
3
Structure of an antibody combining site by magnetic resonance.通过磁共振解析抗体结合位点的结构。
Nature. 1977 Mar 3;266(5597):31-7. doi: 10.1038/266031a0.
4
The distance between the contact sites for DNP and menadione ligands in the combining region of myeloma proteins binding both haptens--II. Estimation of distance using haptenic probes with variable length spacers.骨髓瘤蛋白结合两种半抗原的结合区域中，二硝基苯酚（DNP）和甲萘醌配体结合位点之间的距离——II. 使用带有可变长度间隔臂的半抗原探针估算距离
Immunochemistry. 1976 Nov;13(11):939-43. doi: 10.1016/0019-2791(76)90238-x.
5
Antigen-binding myeloma proteins of mice.小鼠的抗原结合骨髓瘤蛋白
Adv Immunol. 1977;25:141-211.
6
The distance between the contact sites for DNP and menadione ligands in the combining region of myeloma proteins binding both haptens--I. Estimation of distance by fluorescent energy transfer in protein 460.骨髓瘤蛋白结合两种半抗原的结合区域中，二硝基苯酚（DNP）和甲萘醌配体的接触位点之间的距离——I. 通过蛋白质460中的荧光能量转移估算距离
Immunochemistry. 1976 Nov;13(11):929-37. doi: 10.1016/0019-2791(76)90237-8.
7
Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. I. Mapping of genes for Id-460 expression to the variable region of immunoglobulin heavy-chain locus and to the variable region of immunoglobulin kappa-light-chain locus.体内抗二硝基苯基抗体应答过程中独特型（Id-460）的表达。I. 将Id-460表达基因定位到免疫球蛋白重链基因座的可变区以及免疫球蛋白κ轻链基因座的可变区。
J Exp Med. 1980 Sep 1;152(3):720-9. doi: 10.1084/jem.152.3.720.
8
On the role of Tyr 34L in the antibody combining site of the dinitrophenyl binding protein 315.关于酪氨酸34L在二硝基苯基结合蛋白315抗体结合位点中的作用
Mol Immunol. 1979 Nov;16(11):957-63. doi: 10.1016/0161-5890(79)90097-x.
9
The role of nitro groups in the binding of nitroaromatics to protein MOPC 315.硝基在硝基芳烃与蛋白MOPC 315结合中的作用。
Biochem J. 1978 Sep 1;173(3):713-22. doi: 10.1042/bj1730713.
10
The location and expression of idiotypic determinants in the immunoglobulin variable region--III. Expression of the protein 315 and 460 idiotypic determinants in mouse anti-Dnp antibodies.免疫球蛋白可变区中独特型决定簇的定位与表达——III. 小鼠抗二硝基苯（Dnp）抗体中蛋白315和460独特型决定簇的表达
Mol Immunol. 1979 Sep;16(9):657-64. doi: 10.1016/0161-5890(79)90005-1.

引用本文的文献

1
Evidence indicating independent assortment of framework and complementarity-determining segments of the variable regions of rabbit light chains. Delineation of a possible J minigene.表明兔轻链可变区框架区和互补决定区独立排列的证据。一个可能的J小基因的描绘。
J Exp Med. 1980 Jul 1;152(1):72-84. doi: 10.1084/jem.152.1.72.
2
Diversity at the variable-joining region boundary of lambda light chains has a pronounced effect on immunoglobulin ligand-binding activity.λ轻链可变区与连接区边界处的多样性对免疫球蛋白配体结合活性有显著影响。
Proc Natl Acad Sci U S A. 1984 Oct;81(19):6139-43. doi: 10.1073/pnas.81.19.6139.
3
Structural correlates of immunoglobulin diversity.
免疫球蛋白多样性的结构关联
Surv Immunol Res. 1983;2(1):27-42. doi: 10.1007/BF02918394.
4
Members of novel VH gene families are found in VDJ regions of polyclonally activated B-lymphocytes.新型VH基因家族的成员存在于多克隆激活的B淋巴细胞的VDJ区域中。
EMBO J. 1985 Nov;4(11):2861-7. doi: 10.1002/j.1460-2075.1985.tb04015.x.
5
Model-building study of the combining sites of two antibodies to alpha (1----6)dextran.两种抗α(1→6)葡聚糖抗体结合位点的模型构建研究
Proc Natl Acad Sci U S A. 1988 Sep;85(18):6885-9. doi: 10.1073/pnas.85.18.6885.
6
Modelling of the combining sites of three anti-lysozyme monoclonal antibodies and of the complex between one of the antibodies and its epitope.三种抗溶菌酶单克隆抗体结合位点及其一种抗体与其表位之间复合物的建模。
EMBO J. 1986 Feb;5(2):415-25. doi: 10.1002/j.1460-2075.1986.tb04227.x.
7
Nucleotide sequences of five anti-lysozyme monoclonal antibodies.五种抗溶菌酶单克隆抗体的核苷酸序列。
EMBO J. 1985 Feb;4(2):393-8. doi: 10.1002/j.1460-2075.1985.tb03641.x.
8
Three distinct epitopes within the loop region of hen egg lysozyme defined with monoclonal antibodies.用单克隆抗体确定了鸡卵溶菌酶环区的三个不同表位。
EMBO J. 1985 Feb;4(2):383-92. doi: 10.1002/j.1460-2075.1985.tb03640.x.
9
Endogenous peptides of a soluble major histocompatibility complex class I molecule, H-2Lds: sequence motif, quantitative binding, and molecular modeling of the complex.可溶性主要组织相容性复合体I类分子H-2Lds的内源性肽：序列基序、定量结合及复合物的分子建模
J Exp Med. 1992 Dec 1;176(6):1681-92. doi: 10.1084/jem.176.6.1681.
10
Resonance Raman-spectroscopic studies of the hapten features involved in the binding of 2,4-dinitrophenyl haptens by the mouse myeloma proteins MOPC 315 and MOPC 460.对小鼠骨髓瘤蛋白MOPC 315和MOPC 460与2,4-二硝基苯基半抗原结合所涉及的半抗原特征进行共振拉曼光谱研究。
Biochem J. 1978 Nov 1;175(2):727-35. doi: 10.1042/bj1750727.