Nakajima Hiroo, Yamaguchi Yoshiaki, Yoshimura Takashi, Fukumoto Manabu, Todo Takeshi
Department of Radiation Biology and Medical Genetics, Graduate School of Medicine, Osaka University, 2-2, B4, Yamada-Oka, Suita, Osaka 565-0871, Japan
Radioisotope Research Center, Osaka University, 2-4, B4, Yamada-Oka, Suita, Osaka 565-0871, Japan.
J Radiat Res. 2015 Dec;56 Suppl 1(Suppl 1):i29-35. doi: 10.1093/jrr/rrv079.
To investigate the transgenerational effects of chronic low-dose-rate internal radiation exposure after the Fukushima Daiichi Nuclear Power Plant accident in Japan, 18 generations of mice were maintained in a radioisotope facility, with free access to drinking water containing (137)CsCl (0 and 100 Bq/ml). The (137)Cs distribution in the organs of the mice was measured after long-term ad libitum intake of the (137)CsCl water. The litter size and the sex ratio of the group ingesting the (137)Cs water were compared with those of the control group, for all 18 generations of mice. No significant difference was noted in the litter size or the sex ratio between the mice in the control group and those in the group ingesting the (137)Cs water. The fixed internal exposure doses were ∼160 Bq/g and 80 Bq/g in the muscles and other organs, respectively.
为研究日本福岛第一核电站事故后慢性低剂量率内照射的跨代效应，在放射性同位素设施中饲养了18代小鼠，小鼠可自由饮用含有(137)CsCl（0和100 Bq/ml）的水。在长期随意摄入含(137)CsCl的水后，测量了小鼠各器官中的(137)Cs分布。比较了18代摄入(137)Cs水的小鼠组与对照组的产仔数和性别比例。对照组小鼠与摄入(137)Cs水的小鼠组之间在产仔数或性别比例上未观察到显著差异。肌肉和其他器官中的固定内照射剂量分别约为160 Bq/g和80 Bq/g。
