Laloyaux Julien, Dessart Grégory, Van der Linden Martial, Lemaire Morgan, Larøi Frank
a Department of Psychology , University of Liège , Liège , Belgium.
b Faculty of Theology and Religious Studies , Institute for Social Sciences of Contemporary Religions, University of Lausanne , Lausanne , Switzerland.
Cogn Neuropsychiatry. 2016;21(2):116-29. doi: 10.1080/13546805.2015.1137213. Epub 2016 Feb 1.
There is now solid evidence for a relation between adverse life events (ALE) and psychotic symptoms in patients with psychosis and in the general population. A recent study has shown that this relation may be partially mediated by stress sensitivity, suggesting the influence of other factors. The aim of this study was to assess the mediation effect of emotion regulation strategies and stress sensitivity in the relation between ALE and attenuated positive psychotic symptoms (APPS) in the general population.
Hundred and twelve healthy volunteers were evaluated with measures of APPS, emotion regulation strategies, ALE and stress sensitivity.
Results demonstrated that the relation between ALE, hallucination and delusion proneness was completely mediated by maladaptive emotion regulation strategies, but not by stress sensitivity. However, in addition to maladaptive emotion regulation strategies, stress sensitivity demonstrated a mediation effect between ALE and attenuated positive psychotic positive symptoms when positive psychotic symptoms were grouped together.
There are probably several possible trajectories leading to the formation of positive psychotic symptoms and the results of the present study reveal that one such trajectory may involve the maladaptive regulation of negative emotions alongside a certain general vulnerability after experiencing ALE.
目前有确凿证据表明，不良生活事件（ALE）与精神病患者及普通人群的精神病症状之间存在关联。最近一项研究表明，这种关联可能部分由应激敏感性介导，这暗示了其他因素的影响。本研究的目的是评估情绪调节策略和应激敏感性在普通人群中ALE与轻度阳性精神病症状（APPS）之间关系的中介作用。
对112名健康志愿者进行了APPS、情绪调节策略、ALE和应激敏感性的测量评估。
结果表明，ALE与幻觉及妄想倾向之间的关系完全由适应不良的情绪调节策略介导，而非应激敏感性。然而，当将阳性精神病症状归为一组时，除了适应不良的情绪调节策略外，应激敏感性在ALE与轻度阳性精神病阳性症状之间也显示出中介作用。
可能存在多种导致阳性精神病症状形成的轨迹，本研究结果表明，其中一种轨迹可能涉及在经历ALE后，负面情绪的适应不良调节以及某种一般易感性。
