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孤立的乙肝核心抗体与HIV/HCV感染中的晚期肝纤维化相关,但仅在HIV感染中不相关。

Isolated Hepatitis B Core Antibody is Associated With Advanced Hepatic Fibrosis in HIV/HCV Infection But Not in HIV Infection Alone.

作者信息

Bhattacharya Debika, Tseng Chi-Hong, Tate Janet P, Lo Re Vincent, Gibert Cynthia L, Butt Adeel A, Brown Sheldon T, Lim Joseph K, Rodriguez-Barradas Maria C, Rimland David, Kaufman Erica, Justice Amy C, Goetz Matthew Bidwell

机构信息

*VA Greater Los Angeles Healthcare System, Los Angeles, CA †David Geffen School of Medicine, UCLA, Los Angeles, CA ‡VA Connecticut Healthcare System, West Haven, CT §Yale University School of Medicine, New Haven, CT ‖Philadelphia VA Medical Center, Philadelphia, PA ¶Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA #Washington DC VA Medical Center, Washington, DC **George Washington University Medical Center, Washington, DC ††Hamad Healthcare Quality Institute and Hamad Medical Corporation, Doha, Qatar ‡‡VA Pittsburgh Healthcare System, Pittsburgh, PA §§James J. Peters VA Medical Center, Bronx, NY ‖‖Icahn School of Medicine at Mt. Sinai, New York, NY ¶¶Michael E. DeBakey VA Medical Center, Houston, TX ##Baylor College of Medicine, Houston, TX ***Atlanta VA Medical Center, Atlanta, GA †††Emory University School of Medicine, Atlanta, GA ‡‡‡Saint Louis University School of Medicine, Saint Louis, MO.

出版信息

J Acquir Immune Defic Syndr. 2016 May 1;72(1):e14-7. doi: 10.1097/QAI.0000000000000941.

Abstract

HIV+/HCV+ persons with isolated HBcAb have a higher prevalence of advanced fibrosis than persons who are non-immune to HBV, who have resolved HBV, or who are HbsAb+ only.

摘要

与对乙肝病毒无免疫力、已清除乙肝病毒或仅乙肝表面抗体阳性的人相比,孤立性乙肝核心抗体阳性的HIV/HCV合并感染者发生晚期肝纤维化的几率更高。

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