英国生物银行的心血管磁共振检查方案。
UK Biobank's cardiovascular magnetic resonance protocol.
作者信息
Petersen Steffen E, Matthews Paul M, Francis Jane M, Robson Matthew D, Zemrak Filip, Boubertakh Redha, Young Alistair A, Hudson Sarah, Weale Peter, Garratt Steve, Collins Rory, Piechnik Stefan, Neubauer Stefan
机构信息
William Harvey Research Institute, NIHR Cardiovascular Biomedical Research Unit at Barts, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Division of Brain Sciences, Department of Medicine, Imperial College, London, UK.
出版信息
J Cardiovasc Magn Reson. 2016 Feb 1;18:8. doi: 10.1186/s12968-016-0227-4.
BACKGROUND
UK Biobank's ambitious aim is to perform cardiovascular magnetic resonance (CMR) in 100,000 people previously recruited into this prospective cohort study of half a million 40-69 year-olds.
METHODS/DESIGN: We describe the CMR protocol applied in UK Biobank's pilot phase, which will be extended into the main phase with three centres using the same equipment and protocols. The CMR protocol includes white blood CMR (sagittal anatomy, coronary and transverse anatomy), cine CMR (long axis cines, short axis cines of the ventricles, coronal LVOT cine), strain CMR (tagging), flow CMR (aortic valve flow) and parametric CMR (native T1 map).
DISCUSSION
This report will serve as a reference to researchers intending to use the UK Biobank resource or to replicate the UK Biobank cardiovascular magnetic resonance protocol in different settings.
背景
英国生物银行的宏伟目标是，对先前招募到这项针对50万40至69岁人群的前瞻性队列研究中的10万人进行心血管磁共振成像（CMR）检查。
方法/设计：我们描述了英国生物银行试点阶段所应用的CMR方案，该方案将在三个使用相同设备和方案的中心扩展到主要阶段。CMR方案包括白血CMR（矢状位解剖、冠状动脉和横断位解剖）、电影CMR（长轴电影、心室短轴电影、冠状位左心室流出道电影）、应变CMR（标记）、血流CMR（主动脉瓣血流）和参数化CMR（固有T1图谱）。
讨论
本报告将为有意使用英国生物银行资源或在不同环境中复制英国生物银行心血管磁共振方案的研究人员提供参考。
Zotero 插件