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在垂直性牙槽嵴骨量不足时采用骨环技术进行单阶段与两阶段种植体植入——第1部分:组织形态计量学和显微CT分析

Single-staged vs. two-staged implant placement using bone ring technique in vertically deficient alveolar ridges - Part 1: histomorphometric and micro-CT analysis.

作者信息

Nakahara Ken, Haga-Tsujimura Maiko, Sawada Kosaku, Kobayashi Eizaburo, Mottini Matthias, Schaller Benoit, Saulacic Nikola

机构信息

Advanced Research Center, School of Life Dentistry at Niigata, The Nippon Dental University, Niigata, Japan.

Department of Histology, School of Life Dentistry at Niigata, The Nippon Dental University, Niigata, Japan.

出版信息

Clin Oral Implants Res. 2016 Nov;27(11):1384-1391. doi: 10.1111/clr.12751. Epub 2016 Feb 1.

Abstract

BACKGROUND

Simultaneous implant placement with bone grafting shortens the overall treatment period, but might lead to the peri-implant bone loss or even implant failure. The aim of this study was to compare the single-staged to two-staged implant placement using the bone ring technique.

MATERIAL AND METHODS

Four standardized alveolar bone defects were made in the mandibles of nine dogs. Dental implants (Straumann BL , Basel, Switzerland) were inserted simultaneously with bone ring technique in test group and after 6 months of healing period in control group. Animals of both groups were euthanized at 3 and 6 months of osseointegration period. The harvested samples were analyzed by means of histology and micro-CT.

RESULTS

The amount of residual bone decreased while the amount of new bone increased up to 9 months of healing period. All morphometric parameters remained stable between 3 and 6 months of osseointegration period within groups. Per a given time point, median area of residual bone graft was higher in test group and area of new bone in control group. The volume of bone ring was greater in test than in control group, reaching the significance at 6 months of osseointegration period (P = 0.002).

CONCLUSIONS

In the present type of bone defect, single-staged implant placement may be potentially useful to shorten an overall treatment period.

摘要

背景

同期种植体植入并植骨可缩短整体治疗周期,但可能导致种植体周围骨吸收甚至种植失败。本研究的目的是比较采用骨环技术的一期种植与二期种植。

材料与方法

在9只犬的下颌骨上制作4个标准化牙槽骨缺损。试验组采用骨环技术同期植入牙种植体(瑞士巴塞尔士卓曼BL),对照组在愈合6个月后植入。在骨整合期3个月和6个月时对两组动物实施安乐死。对采集的样本进行组织学和显微CT分析。

结果

至愈合9个月时,剩余骨量减少,新骨量增加。在组内骨整合期3个月至6个月期间,所有形态学参数均保持稳定。在给定的时间点,试验组剩余骨移植的中位面积较高,对照组新骨面积较高。试验组骨环体积大于对照组,在骨整合期6个月时达到显著性差异(P = 0.002)。

结论

在本类型骨缺损中,一期种植体植入可能有助于缩短整体治疗周期。

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