与子宫内膜异位症相关的营养因素。

Nutritional aspects related to endometriosis.

作者信息

Halpern Gabriela, Schor Eduardo, Kopelman Alexander

机构信息

Department of Gynecology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Department of Gynecology, Escola Paulista de Medicina, Unifesp, São Paulo, SP, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2015 Nov-Dec;61(6):519-23. doi: 10.1590/1806-9282.61.06.519.

Abstract

This literature review analyzed the evidence on nutritional aspects related to the pathogenesis and progression of endometriosis. Diets deficient in nutrients result in changes in lipid metabolism, oxidative stress and promote epigenetic abnormalities, that may be involved in the genesis and progression of the disease. Foods rich in omega 3 with anti-inflammatory effects, supplementation with N-acetylcysteine, vitamin D and resveratrol, in addition to the increased consumption of fruits, vegetables (preferably organic) and whole grains exert a protective effect, reducing the risk of development and possible regression of disease. Dietary re-education seems to be a promising tool in the prevention and treatment of endometriosis.

摘要

这篇文献综述分析了与子宫内膜异位症发病机制和进展相关的营养方面的证据。营养缺乏的饮食会导致脂质代谢、氧化应激的变化,并促进表观遗传异常,这些可能与该疾病的发生和进展有关。富含具有抗炎作用的omega-3的食物、补充N-乙酰半胱氨酸、维生素D和白藜芦醇,以及增加水果、蔬菜(最好是有机的)和全谷物的摄入量,都具有保护作用,可降低疾病发展的风险以及可能的病情逆转。饮食再教育似乎是预防和治疗子宫内膜异位症的一个有前景的工具。

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