Goldstein E J
R. M. Alden Research Laboratory, Santa Monica Hospital Medical Center, CA 90404.
J Am Acad Dermatol. 1989 Dec;21(6):1275-9. doi: 10.1016/s0190-9622(89)70343-1.
Bite wounds, usually by dogs, cats, and human beings, affect one of two Americans during his or her lifetime and 1 to 2 million Americans annually. Despite the relative frequency of bite wounds, there are few prospective studies to define optimal care; consequently, diverse methods are used. In this article I review the incidence, bacteriology, clinical spectrum, complications, and treatment of animal and human bite wounds. The spectrum of pathogenic bacteria that cause bite infections is broader than is generally appreciated and includes both aerobic and anaerobic bacteria. Pasteurella multocida is found in only 20% to 25% of dog bite wounds. In choosing empiric antimicrobial therapy, clinicians must consider the diverse causative bacteria and their characteristic susceptibility patterns. Liberal irrigation and elevation of the injured part are also cornerstones of therapy. Early, aggressive medical and surgical management can minimize, if not prevent, complications.
咬伤伤口通常由狗、猫和人造成,在美国,每两个人中就有一人一生中会受到咬伤,每年有100万至200万美国人被咬伤。尽管咬伤伤口相对常见,但很少有前瞻性研究来确定最佳治疗方法;因此,人们使用了各种各样的方法。在本文中,我将回顾动物和人类咬伤伤口的发病率、细菌学、临床症状、并发症及治疗方法。导致咬伤感染的病原菌谱比一般认为的要广,包括需氧菌和厌氧菌。多杀巴斯德菌仅在20%至25%的狗咬伤伤口中被发现。在选择经验性抗菌治疗时,临床医生必须考虑多种致病细菌及其特征性药敏模式。充分冲洗和抬高受伤部位也是治疗的基石。早期积极的药物和手术治疗即使不能预防并发症,也可将其危害降至最低。