Department of Nano Bio Research, National NanoFab Center (NNFC), Daejeon 305-806, Republic of Korea.
Department of Chemical & Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.
Biosens Bioelectron. 2017 Mar 15;89(Pt 1):612-619. doi: 10.1016/j.bios.2016.01.075. Epub 2016 Jan 29.
The integration of organic and inorganic building blocks into hierarchical porous architectures makes potentially desirable electrocatalytic materials in many electrochemical applications due to their combination of attractive qualities of dissimilar components and well-constructed charge transfer pathways. Herein, we demonstrate the preparation of the hierarchical porous CoO@graphene (CoO@G) microspheres by one-step hydrothermal method to achieve high electrocatalytic performance for enzyme-free biosensor applications. The obtained CoO@G microspheres are consisted of the interconnected networks of CoO and graphene sheets, and thus provide large accessible active sites through porous structure, while graphene sheets offer continuous electron pathways for efficient electrocatalytic reaction of CoO. These structural merits with synergy effect of CoO and graphene lead to a high performance of enzyme-free detection for glucose: high sensitivity, good selectivity, and remarkable stability.
将有机和无机构建块集成到分级多孔结构中，由于不同成分的吸引力和精心构建的电荷转移途径的结合，使它们成为许多电化学应用中潜在理想的电催化材料。在此，我们通过一步水热法制备了分级多孔 CoO@graphene（CoO@G）微球，以实现用于无酶生物传感器应用的高电催化性能。所得到的 CoO@G 微球由 CoO 和石墨烯片的相互连接的网络组成，因此通过多孔结构提供了大量可及的活性位点，而石墨烯片则为 CoO 的有效电催化反应提供了连续的电子途径。这些结构优点与 CoO 和石墨烯的协同作用导致无酶检测葡萄糖具有高的性能：高灵敏度、良好的选择性和显著的稳定性。
