Teruel Carlos, Garrido Elena, Mesonero Francisco
Carlos Teruel, Elena Garrido, Francisco Mesonero, Gastroenterology Department, Hospital Ramón y Cajal, 28034 Madrid, Spain.
World J Gastrointest Pharmacol Ther. 2016 Feb 6;7(1):78-90. doi: 10.4292/wjgpt.v7.i1.78.
Inflammatory bowel disease (IBD) patients in remission may suffer from gastrointestinal symptoms that resemble irritable bowel syndrome (IBS). Knowledge on this issue has increased considerably in the last decade, and it is our intention to review and summarize it in the present work. We describe a problematic that comprises physiopathological uncertainties, diagnostic difficulties, as IBS-like symptoms are very similar to those produced by an inflammatory flare, and the necessity of appropriate management of these patients, who, although in remission, have impaired quality of life. Ultimately, from almost a philosophical point of view, the presence of IBS-like symptoms in IBD patients in remission supposes a challenge to the traditional functional-organic dichotomy, suggesting the need for a change of paradigm.
炎症性肠病(IBD)缓解期患者可能会出现类似肠易激综合征(IBS)的胃肠道症状。在过去十年中,关于这个问题的认识有了显著提高,我们打算在本研究中对其进行回顾和总结。我们描述了一个存在生理病理不确定性、诊断困难的问题,因为IBS样症状与炎症发作产生的症状非常相似,并且有必要对这些患者进行适当管理,尽管他们处于缓解期,但生活质量仍受到损害。最终,从几乎是哲学的角度来看,IBD缓解期患者出现IBS样症状对传统的功能性-器质性二分法提出了挑战,表明需要改变范式。