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Retinoids and vertebrate limb pattern formation.

作者信息

Eichele G

出版信息

Trends Genet. 1989 Aug;5(8):246-51. doi: 10.1016/0168-9525(89)90096-6.

DOI:10.1016/0168-9525(89)90096-6
PMID:2686112
Abstract

It has long been suggested that pattern formation depends in part on signalling molecules known as 'morphogens', diffusible substances that determine cell fate in a concentration-dependent way. Retinoic acid, a small hydrophobic molecule that binds to nuclear receptors, is a candidate morphogen for specifying the anteroposterior pattern of vertebrate limbs.

摘要

相似文献

1
Retinoids and vertebrate limb pattern formation.
Trends Genet. 1989 Aug;5(8):246-51. doi: 10.1016/0168-9525(89)90096-6.
2
Molecular approaches to vertebrate limb morphogenesis.脊椎动物肢体形态发生的分子学方法。
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3
Morphogens in chick limb development.鸡胚肢体发育中的形态发生素
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Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud.视黄酸诱导极化活性,但不太可能是鸡胚肢芽中的形态发生素。
Nature. 1991 Mar 7;350(6313):83-6. doi: 10.1038/350083a0.
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Isolation of 3,4-didehydroretinoic acid, a novel morphogenetic signal in the chick wing bud.3,4-二脱氢视黄酸的分离,一种鸡胚翅芽中的新型形态发生信号。
Nature. 1990 Jun 28;345(6278):815-9. doi: 10.1038/345815a0.
6
Recent progress in vertebrate limb morphogenesis.脊椎动物肢体形态发生的最新进展。
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Polarizing activity and retinoid synthesis in the floor plate of the neural tube.神经管底板中的极化活性与类视黄醇合成
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Distribution of retinoids in the chick limb bud: analysis with monoclonal antibody.维甲酸在鸡胚肢芽中的分布:用单克隆抗体进行分析
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Spatial distribution of cellular protein binding to retinoic acid in the chick limb bud.鸡胚肢体芽中细胞蛋白与视黄酸结合的空间分布。
Nature. 1988 Oct 20;335(6192):733-5. doi: 10.1038/335733a0.

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