Frings Andreas, Markau Nastassija, Katz Toam, Stemplewitz Birthe, Skevas Christos, Druchkiv Vasyl, Wagenfeld Lars
Department of Ophthalmology, University Medical Centre Hamburg-Eppendorf (UKE), Hamburg, Germany.
Care Vision Refractive Centres, Hamburg, Germany.
Br J Ophthalmol. 2016 Nov;100(11):1466-1469. doi: 10.1136/bjophthalmol-2015-308153. Epub 2016 Feb 11.
To investigate the influence of lag time between the onset of central visual acuity loss and surgical intervention of macula-off retinal detachment.
This retrospective case series examined all consecutively treated eyes with primary macula-off retinal detachment at the University Hospital Hamburg (Germany) from February 2010 to February 2015. Records of 1727 patients operated by six surgeons were reviewed. Eighty-nine eyes (5.2%) from 89 patients met the inclusion and exclusion criteria. The main outcome measure studied was final visual acuity as a function of symptom duration of macula-off detachment. Secondary outcome measures studied were influence of age and surgical technique. Symptom duration was defined as the time from the onset of loss of central vision to surgical intervention.
After 10 days no clinically relevant difference was seen in final visual acuity. Eyes with symptom duration of 3 days or less achieved best final visual acuity (p<0.001). Age and preoperative visual acuity had no influence while vitrectomised eyes had better outcome compared with those with scleral buckling.
Our study suggests that 1. After 10 days of central visual acuity loss, the final visual outcome is clinically comparable and independent of further delay of surgery up to 30 days. 2. Eyes treated up to 3 days after onset of loss of central vision have better final visual acuity than eyes with longer lag time. However, we did not find statistically significant differences within the first 3 days. 3. Surgery for macula-off retinal detachment may therefore most likely be postponed without compromising the patient's visual prognosis.
探讨中心视力丧失至黄斑脱离视网膜手术干预之间的间隔时间的影响。
本回顾性病例系列研究了2010年2月至2015年2月在德国汉堡大学医院连续接受治疗的原发性黄斑脱离视网膜的所有眼睛。回顾了由六位外科医生手术的1727例患者的记录。89例患者的89只眼(5.2%)符合纳入和排除标准。研究的主要结局指标是最终视力作为黄斑脱离症状持续时间的函数。研究的次要结局指标是年龄和手术技术的影响。症状持续时间定义为从中心视力丧失开始至手术干预的时间。
10天后,最终视力未见临床相关差异。症状持续时间为3天或更短的眼睛获得了最佳最终视力(p<0.001)。年龄和术前视力无影响,而玻璃体切除的眼睛与巩膜扣带术的眼睛相比结局更好。
我们的研究表明:1. 中心视力丧失10天后,最终视力结局在临床上具有可比性,且在长达30天的时间内与手术进一步延迟无关。2. 中心视力丧失后3天内接受治疗的眼睛比延迟时间更长的眼睛具有更好的最终视力。然而,我们在头3天内未发现统计学上的显著差异。3. 因此,黄斑脱离视网膜手术很可能可以推迟而不影响患者的视觉预后。