Ganesh Sri, Brar Sheetal
Department of Phaco and Refractive Surgeries, Nethradhama Superspeciality Eye Hospital, Bangalore, India.
Clin Ophthalmol. 2016 Jan 27;10:207-11. doi: 10.2147/OPTH.S89487. eCollection 2016.
To compare the effect of two ocular viscosurgical devices (OVDs) on intraocular pressure (IOP) and surgical time in immediate postoperative period after bilateral implantable collamer lens (using the V4c model) implantation.
A total of 20 eligible patients were randomized to receive 2% hydroxypropylmethylcellulose (HPMC) in one eye and 1% hyaluronic acid in fellow eye. Time taken for complete removal of OVD and total surgical time were recorded. At the end of surgery, IOP was adjusted between 15 and 20 mmHg in both the eyes.
Mean time for complete OVD evacuation and total surgical time were significantly higher in the HPMC group (P=0.00). Four eyes in the HPMC group had IOP spike, requiring treatment. IOP values with noncontact tonometry at 1, 2, 4, 24, and 48 hours were not statistically significant (P>0.05) for both the groups.
The study concluded that 1% hyaluronic acid significantly reduces total surgical time, and incidence of acute spikes may be lower compared to 2% HPMC when used for implantable collamer lens (V4c model).
比较两种眼科粘弹剂(OVDs)对双侧植入式角膜接触镜(使用V4c模型)植入术后即刻眼压(IOP)和手术时间的影响。
总共20例符合条件的患者被随机分为一只眼使用2%羟丙基甲基纤维素(HPMC),另一只眼使用1%透明质酸。记录完全清除OVD所需的时间和总手术时间。手术结束时,双眼眼压均调整至15至20 mmHg之间。
HPMC组完全清除OVD的平均时间和总手术时间显著更长(P = 0.00)。HPMC组有4只眼出现眼压峰值,需要治疗。两组在1、2、4、24和48小时使用非接触眼压计测量的眼压值无统计学差异(P>0.05)。
该研究得出结论,当用于植入式角膜接触镜(V4c模型)时,1%透明质酸可显著缩短总手术时间,且急性眼压峰值的发生率可能低于2% HPMC。