Who Is Leading the Replication Fork, Pol ε or Pol δ?
作者信息
Burgers Peter M J, Gordenin Dmitry, Kunkel Thomas A
机构信息
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC 27709, USA.
出版信息
Mol Cell. 2016 Feb 18;61(4):492-493. doi: 10.1016/j.molcel.2016.01.017.
Abstract
摘要
相似文献
1
Who Is Leading the Replication Fork, Pol ε or Pol δ?谁在引领复制叉，聚合酶ε还是聚合酶δ？
Mol Cell. 2016 Feb 18;61(4):492-493. doi: 10.1016/j.molcel.2016.01.017.
2
Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes.重新审视真核生物复制叉处的DNA聚合酶
Mol Cell. 2015 Jul 16;59(2):139-41. doi: 10.1016/j.molcel.2015.07.004.
3
Quality control mechanisms exclude incorrect polymerases from the eukaryotic replication fork.质量控制机制将错误的聚合酶排除在真核生物复制叉之外。
Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):675-680. doi: 10.1073/pnas.1619748114. Epub 2017 Jan 9.
4
Both DNA Polymerases δ and ε Contact Active and Stalled Replication Forks Differently.DNA聚合酶δ和ε与活跃的和停滞的复制叉的接触方式不同。
Mol Cell Biol. 2017 Oct 13;37(21). doi: 10.1128/MCB.00190-17. Print 2017 Nov 1.
5
Response to Burgers et al.对伯格斯等人的回应
Mol Cell. 2016 Feb 18;61(4):494-495. doi: 10.1016/j.molcel.2016.01.018.
6
Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae.酿酒酵母中DNA聚合酶α、δ和ε协调染色体复制所需的遗传网络。
G3 (Bethesda). 2015 Aug 21;5(10):2187-97. doi: 10.1534/g3.115.021493.
7
How asymmetric DNA replication achieves symmetrical fidelity.不对称 DNA 复制如何实现对称保真度。
Nat Struct Mol Biol. 2021 Dec;28(12):1020-1028. doi: 10.1038/s41594-021-00691-6. Epub 2021 Dec 9.
8
A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands.DNA聚合酶δ在DNA前导链和滞后链复制中的主要作用
Mol Cell. 2015 Jul 16;59(2):163-175. doi: 10.1016/j.molcel.2015.05.038. Epub 2015 Jul 2.
9
Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation.真核生物复制体的重组揭示了定义前导链/后随链运作的抑制机制。
Elife. 2015 Apr 14;4:e04988. doi: 10.7554/eLife.04988.
10
Chromatin Constrains the Initiation and Elongation of DNA Replication.染色质限制DNA复制的起始和延伸。
Mol Cell. 2017 Jan 5;65(1):131-141. doi: 10.1016/j.molcel.2016.10.035. Epub 2016 Dec 15.
引用本文的文献
1
Strand-resolved mutagenicity of DNA damage and repair.DNA 损伤与修复的链分辨致突变性。
Nature. 2024 Jun;630(8017):744-751. doi: 10.1038/s41586-024-07490-1. Epub 2024 Jun 12.
2
Polymorphism of Strains in DNA Metabolism Genes.DNA 代谢基因菌株的多态性。
Int J Mol Sci. 2023 Apr 25;24(9):7795. doi: 10.3390/ijms24097795.
3
Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases.建立 DNA 损伤、突变和遗传疾病之间的联系。
Chem Res Toxicol. 2022 Oct 17;35(10):1655-1675. doi: 10.1021/acs.chemrestox.2c00155. Epub 2022 Jul 26.
4
Germline and proofreading domain mutations in endometrial carcinoma from Middle Eastern region.中东地区子宫内膜癌中的种系和校对结构域突变
Cancer Cell Int. 2019 Dec 11;19:334. doi: 10.1186/s12935-019-1058-9. eCollection 2019.
5
Structure and function relationships in mammalian DNA polymerases.哺乳动物 DNA 聚合酶的结构与功能关系。
Cell Mol Life Sci. 2020 Jan;77(1):35-59. doi: 10.1007/s00018-019-03368-y. Epub 2019 Nov 13.
6
Plant DNA Polymerases.植物 DNA 聚合酶。
Int J Mol Sci. 2019 Sep 27;20(19):4814. doi: 10.3390/ijms20194814.
7
DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.干细胞中的 DNA 损伤容忍、衰老、突变、疾病和癌症治疗。
Nucleic Acids Res. 2019 Aug 22;47(14):7163-7181. doi: 10.1093/nar/gkz531.
8
DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in .DNA 复制通过滞后链 DNA 合成中的链置换。
Genes (Basel). 2019 Feb 21;10(2):167. doi: 10.3390/genes10020167.
9
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.一种在 DNA 聚合酶 ε 中反复出现的与癌症相关的取代会产生一种超活性酶。
Nat Commun. 2019 Jan 22;10(1):374. doi: 10.1038/s41467-018-08145-2.
10
DNA Damage, Mutagenesis and Cancer.DNA 损伤、突变与癌症。
Int J Mol Sci. 2018 Mar 23;19(4):970. doi: 10.3390/ijms19040970.
本文引用的文献
1
A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands.DNA聚合酶δ在DNA前导链和滞后链复制中的主要作用
Mol Cell. 2015 Jul 16;59(2):163-175. doi: 10.1016/j.molcel.2015.05.038. Epub 2015 Jul 2.
2
Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans.复制性DNA聚合酶δ而非ε校正顺式和反式中的错误。
PLoS Genet. 2015 Mar 5;11(3):e1005049. doi: 10.1371/journal.pgen.1005049. eCollection 2015 Mar.
3
A global profile of replicative polymerase usage.复制性聚合酶使用情况的全球概况。
Nat Struct Mol Biol. 2015 Mar;22(3):192-198. doi: 10.1038/nsmb.2962. Epub 2015 Feb 9.
4
Lagging-strand replication shapes the mutational landscape of the genome.滞后链复制塑造了基因组的突变格局。
Nature. 2015 Feb 26;518(7540):502-506. doi: 10.1038/nature14183. Epub 2015 Jan 26.
5
Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation.通过核糖核苷酸掺入的全基因组定位在体内追踪复制酶学
Nat Struct Mol Biol. 2015 Mar;22(3):185-91. doi: 10.1038/nsmb.2957. Epub 2015 Jan 26.
6
Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA.核糖核苷酸测序：嵌入基因组DNA中的核糖核苷酸的全局定位。
Nat Methods. 2015 Mar;12(3):251-7, 3 p following 257. doi: 10.1038/nmeth.3259. Epub 2015 Jan 26.
7
Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.异质性聚合酶保真度和错配修复影响基因组变异与组成。
Genome Res. 2014 Nov;24(11):1751-64. doi: 10.1101/gr.178335.114. Epub 2014 Sep 12.
8
Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.真核复制叉处不对称聚合酶组装的机制。
Nat Struct Mol Biol. 2014 Aug;21(8):664-70. doi: 10.1038/nsmb.2851. Epub 2014 Jul 6.
9
Dividing the workload at a eukaryotic replication fork.真核生物复制叉处的工作量分配
Trends Cell Biol. 2008 Nov;18(11):521-7. doi: 10.1016/j.tcb.2008.08.005. Epub 2008 Sep 27.
10
Division of labor at the eukaryotic replication fork.真核生物复制叉处的分工。
Mol Cell. 2008 Apr 25;30(2):137-44. doi: 10.1016/j.molcel.2008.02.022.
Zotero 插件