• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Epileptogenesis: More Than Just the Latent Period.

作者信息

Maguire Jamie

出版信息

Epilepsy Curr. 2016 Jan-Feb;16(1):31-3. doi: 10.5698/1535-7597-16.1.31.

DOI:10.5698/1535-7597-16.1.31
PMID:26900375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4749113/
Abstract
摘要

相似文献

1
Epileptogenesis: More Than Just the Latent Period.癫痫发生：不止于潜伏期。
Epilepsy Curr. 2016 Jan-Feb;16(1):31-3. doi: 10.5698/1535-7597-16.1.31.
2
Altered intrinsic functional connectivity in the latent period of epileptogenesis in a temporal lobe epilepsy model.颞叶癫痫模型中癫痫发生潜伏期内内在功能连接的改变。
Exp Neurol. 2017 Oct;296:89-98. doi: 10.1016/j.expneurol.2017.07.007. Epub 2017 Jul 17.
3
Significant effects of sex, strain, and anesthesia in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy.在海马内注射红藻氨酸的内侧颞叶癫痫小鼠模型中，性别、品系和麻醉的显著影响。
Epilepsy Behav. 2016 Feb;55:47-56. doi: 10.1016/j.yebeh.2015.11.027. Epub 2015 Dec 28.
4
The enigma of the latent period in the development of symptomatic acquired epilepsy - Traditional view versus new concepts.症状性获得性癫痫发展中潜伏期之谜——传统观点与新概念
Epilepsy Behav. 2015 Nov;52(Pt A):78-92. doi: 10.1016/j.yebeh.2015.08.037. Epub 2015 Sep 25.
5
Progression of convulsive and nonconvulsive seizures during epileptogenesis after pilocarpine-induced status epilepticus.匹鲁卡品诱导的癫痫持续状态后癫痫发生过程中惊厥性和非惊厥性癫痫发作的进展。
J Neurophysiol. 2018 May 1;119(5):1818-1835. doi: 10.1152/jn.00721.2017. Epub 2018 Feb 14.
6
No latency to dentate granule cell epileptogenesis in experimental temporal lobe epilepsy with hippocampal sclerosis.在伴有海马硬化的实验性颞叶癫痫中，齿状回颗粒细胞癫痫发生无潜伏期。
Epilepsia. 2018 Nov;59(11):2019-2034. doi: 10.1111/epi.14580. Epub 2018 Oct 19.
7
Hyperexcitability of the CA1 hippocampal region during epileptogenesis.癫痫发生过程中海马CA1区的兴奋性过高。
Epilepsia. 2007;48 Suppl 5:131-9. doi: 10.1111/j.1528-1167.2007.01301.x.
8
Protection against cognitive impairment and modification of epileptogenesis with curcumin in a post-status epilepticus model of temporal lobe epilepsy.姜黄素对颞叶癫痫癫痫持续状态后模型认知障碍的保护作用及癫痫发生的改变
Neuroscience. 2015 Dec 3;310:362-71. doi: 10.1016/j.neuroscience.2015.09.058. Epub 2015 Sep 28.
9
Epileptogenesis and companion animals.癫痫发生与伴侣动物。
Top Companion Anim Med. 2013 May;28(2):42-5. doi: 10.1053/j.tcam.2013.06.010.
10
Epileptogenesis meets Occam's Razor.致癫痫发生遇见奥卡姆剃刀。
Curr Opin Pharmacol. 2017 Aug;35:105-110. doi: 10.1016/j.coph.2017.07.012. Epub 2017 Aug 3.

引用本文的文献

1
Neuroprotective Effects of Early TLR4 Blockade with Compound C34 in Temporal Lobe Epilepsy: Alleviation of Neuroinflammation and Apoptosis.早期使用化合物C34阻断TLR4对颞叶癫痫的神经保护作用：减轻神经炎症和细胞凋亡。
Iran J Pharm Res. 2025 Mar 8;24(1):e159165. doi: 10.5812/ijpr-159165. eCollection 2025 Jan-Dec.
2
Molecular Genetics of Acquired Temporal Lobe Epilepsy.获得性颞叶癫痫的分子遗传学。
Biomolecules. 2024 Jun 7;14(6):669. doi: 10.3390/biom14060669.
3
Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy.在小儿癫痫 knockin 小鼠模型中，神经元兴奋性增加引起的生理反应存在性别差异。
Clin Sci (Lond). 2024 Feb 21;138(4):205-223. doi: 10.1042/CS20231572.
4
Astrocytes as a target for therapeutic strategies in epilepsy: current insights.星形胶质细胞作为癫痫治疗策略的靶点：当前见解
Front Mol Neurosci. 2023 Jul 31;16:1183775. doi: 10.3389/fnmol.2023.1183775. eCollection 2023.
5
Capturing the power of seizures: an empirical mode decomposition analysis of epileptic activity in the mouse hippocampus.捕捉癫痫发作的力量：小鼠海马体癫痫活动的经验模态分解分析
Front Mol Neurosci. 2023 May 15;16:1121479. doi: 10.3389/fnmol.2023.1121479. eCollection 2023.
6
Oxidative Stress and Neurodegeneration in Animal Models of Seizures and Epilepsy.癫痫发作和癫痫动物模型中的氧化应激与神经退行性变
Antioxidants (Basel). 2023 May 5;12(5):1049. doi: 10.3390/antiox12051049.
7
Anti-high mobility group box protein 1 monoclonal antibody downregulating P-glycoprotein as novel epilepsy therapeutics.抗高迁移率族蛋白1单克隆抗体下调P-糖蛋白作为新型癫痫治疗药物
Egypt J Neurol Psychiatr Neurosurg. 2022;58(1):121. doi: 10.1186/s41983-022-00557-8. Epub 2022 Oct 22.
8
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.药物诱导 AMFR 增加功能性 EAAT2 寡聚体水平并减少小鼠癫痫发作。
JCI Insight. 2022 Aug 8;7(15):e160247. doi: 10.1172/jci.insight.160247.
9
Latency of poststroke epilepsy can predict drug resistance.脑卒中后癫痫的潜伏期可预测耐药性。
Eur J Neurol. 2022 Aug;29(8):2481-2485. doi: 10.1111/ene.15408. Epub 2022 May 30.
10
Characterizing Hippocampal Oscillatory Signatures Underlying Seizures in Temporal Lobe Epilepsy.颞叶癫痫发作背后海马振荡特征的表征
Front Behav Neurosci. 2021 Nov 25;15:785328. doi: 10.3389/fnbeh.2021.785328. eCollection 2021.

本文引用的文献

1
GABAergic inhibition shapes interictal dynamics in awake epileptic mice.GABA 能抑制作用塑造清醒癫痫小鼠的发作间期动力学。
Brain. 2015 Oct;138(Pt 10):2875-90. doi: 10.1093/brain/awv227. Epub 2015 Aug 13.
2
Evolution of Network Synchronization during Early Epileptogenesis Parallels Synaptic Circuit Alterations.早期癫痫发生过程中网络同步的演变与突触回路改变平行。
J Neurosci. 2015 Jul 8;35(27):9920-34. doi: 10.1523/JNEUROSCI.4007-14.2015.
3
Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction.癫痫发生机制：神经回路功能障碍的汇聚。
Nat Rev Neurosci. 2013 May;14(5):337-49. doi: 10.1038/nrn3482. Epub 2013 Apr 18.
4
Spatially clustered neuronal assemblies comprise the microstructure of synchrony in chronically epileptic networks.空间聚集的神经元集合构成了慢性癫痫网络中同步的微观结构。
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3567-72. doi: 10.1073/pnas.1216958110. Epub 2013 Feb 11.
5
Hippocampal microcircuit dynamics probed using optical imaging approaches.使用光学成像方法探测海马微电路动力学。
J Physiol. 2011 Apr 15;589(Pt 8):1893-903. doi: 10.1113/jphysiol.2010.202184. Epub 2011 Jan 10.
6
Interictal spikes precede ictal discharges in an organotypic hippocampal slice culture model of epileptogenesis.在癫痫发生的器官型海马切片培养模型中，发作间期棘波先于发作放电。
J Clin Neurophysiol. 2010 Dec;27(6):418-24. doi: 10.1097/WNP.0b013e3181fe0709.
7
Epileptogenesis in the immature brain: emerging mechanisms.未成熟脑的癫痫发生：新兴机制。
Nat Rev Neurol. 2009 Jul;5(7):380-91. doi: 10.1038/nrneurol.2009.80.
8
Disrupted dentate granule cell chloride regulation enhances synaptic excitability during development of temporal lobe epilepsy.齿状颗粒细胞氯调节紊乱会增强颞叶癫痫发育过程中的突触兴奋性。
J Neurosci. 2007 Dec 19;27(51):14012-22. doi: 10.1523/JNEUROSCI.4390-07.2007.
9
The progression of epilepsy.癫痫的进展
Epilepsia. 2006;47 Suppl 1:71-8. doi: 10.1111/j.1528-1167.2006.00665.x.
10
Mechanisms of epilepsy progression: current theories and perspectives from neuroplasticity in adulthood and development.癫痫进展的机制：来自成年期和发育过程中神经可塑性的当前理论与观点
Epilepsy Res. 2004 Jul-Aug;60(2-3):161-71. doi: 10.1016/j.eplepsyres.2004.07.001.