Ko Yu-Chieh, Hwang De-Kuang, Chen Wei-Ta, Lee Ching-Chih, Liu Catherine J
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.
Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan.
PLoS One. 2016 Feb 23;11(2):e0149698. doi: 10.1371/journal.pone.0149698. eCollection 2016.
To understand the impact of socioeconomic status (SES) on the diagnosis of primary open-angle glaucoma (POAG) and primary angle closure glaucoma (PACG) in Taiwan.
Subjects with glaucoma were identified from the National Health Insurance Research Database of year 2006, which included one million randomly selected insurants. Individuals who had ≥4 ambulatory visits within one year which had the diagnosis code of POAG (ICD-9-CM 365.11 or 365.12) or PACG (365.23) and concurrent prescription of anti-glaucoma medication or surgery were selected. Individual SES was represented by monthly income calculated from the insurance premium. Neighborhood SES was defined based on neighborhood household income averages. Urbanization level of habitation was categorized into 3 levels. The odds ratio of having POAG or PACG in subjects with different SES was evaluated by using multiple logistic regression analysis.
In total, 752 and 561 subjects with POAG and PACG, respectively, who were treated on a regular basis, were identified. The diagnosis of glaucoma was affected by age, gender, frequency of healthcare utilization, individual SES, and urbanization level of habitation. With the adjustment of age, gender, healthcare utilization, neighborhood SES and level of urbanization, subjects with lower income were more likely to be diagnosed as PACG, but less likely as POAG.
Subjects with more frequent healthcare utilization were more likely to be diagnosed with glaucoma. Subjects with low SES were more susceptible to PACG, but subjects with high SES were more likely to be diagnosed as POAG. This information is useful for the design and target participant setting in glaucoma education and screening campaign to maximize the efficacy of limited resources in preventing glaucoma blindness.
了解社会经济地位(SES)对台湾原发性开角型青光眼(POAG)和原发性闭角型青光眼(PACG)诊断的影响。
从2006年全民健康保险研究数据库中识别青光眼患者,该数据库包含100万随机选取的被保险人。选取在一年内有≥4次门诊就诊记录,诊断代码为POAG(国际疾病分类第九版临床修订本365.11或365.12)或PACG(365.23),并同时开具抗青光眼药物或接受手术治疗的个体。个体SES用根据保险费计算的月收入表示。邻里SES根据邻里家庭平均收入定义。居住的城市化水平分为3个等级。采用多元逻辑回归分析评估不同SES受试者患POAG或PACG的比值比。
共识别出752例定期接受治疗的POAG患者和561例PACG患者。青光眼的诊断受年龄、性别、医疗保健利用频率、个体SES和居住的城市化水平影响。在调整年龄、性别、医疗保健利用、邻里SES和城市化水平后,低收入受试者更易被诊断为PACG,但被诊断为POAG的可能性较小。
医疗保健利用频率较高的受试者更易被诊断为青光眼。SES低的受试者更易患PACG,但SES高的受试者更易被诊断为POAG。这些信息有助于青光眼教育和筛查活动的设计及目标参与者设定,以最大限度提高有限资源预防青光眼致盲的效果。